750588-07-9Relevant academic research and scientific papers
Synthesis and Reactions of Novel Pyrimido[4,5-c]pyridazine and s-Triazolo[3',4':2,3]pyrimido[4,5-c]pyridazine Derivatives
Moneam, Maisa I. Abdel
, p. 45 - 54 (2007/10/03)
The reaction of 3-chloro-5,6-diphenylpyridazine-4-carbonitrile with potassium thiocyanate gave the corresponding isothiocyanate derivative. This was reacted with aromatic amines in ethanol to afford pyrimido[4,5-c]pyridazine derivatives. The reaction of the latter compounds with hydrazine hydrate led to the formation of 6-hydrazino derivatives. One hydrazino compound was reacted with a variety of reagents to produce other new pyrimidopyridazines as well as a number of s-triazolo derivatives.
