7507-08-6Relevant academic research and scientific papers
Synthesis of a phosphinate analogue of the anti-tumour phosphate di-ester perifosine via sequential radical processes
Markoulides, Marios S.,Regan, Andrew C.
, p. 119 - 129 (2013/02/23)
An efficient synthesis of a phosphinate analogue of the anti-tumour phosphate di-ester perifosine is described (6 steps and 50% overall yield). The two phosphorus-carbon bonds in the perifosine analogue were prepared by sequential double radical hydrophosphinylation processes. This is the first example of a phosphinate analogue of perifosine, designed to be resistant to hydrolysis by phospholipid-metabolizing enzymes. The Royal Society of Chemistry.
SYNTHESIS OF ACYCLIC AND CYLIC DIALKYLPHOSPHINIC ACIDS FROM AMMONIUM HYPOPHOSPHITE
Kurdyumova, N. R.,Ragulin, V. V.,Tsvetkov, E. N.
, p. 380 - 383 (2007/10/02)
The possibilities of synthesizing dialkylphosphinic and cyclic phosphinic acids from ammonium hypophosphite, hexamethyldisilazane, and corresponding halogen derivatives have been studied.These acids can be prepared in low yield, but the simplicity of the process compensates for this disadvantage.
Magnetic concentration and polymorphism in di-n-octyl-, di-n-decyl-, and di-n-dodecylphosphinates of copper(II)
Haynes, John S.,Oliver, Katherine W.,Thompson, Robert C.
, p. 1111 - 1117 (2007/10/02)
Phosphinates of copper(II) of the type Cu(R2PO2)2 where R is n-octyl, n-decyl, and n-dodecyl have been synthesized and characterized by differential scanning calorimetry, vibrational and electronic spectroscopy, and variable temperature (300 to 4.2 K) magnetic susceptibility studies.Each of these compounds was obtained in distinct α and β structural forms.All materials appear to have the double phosphinate bridged extended chain structure and the magnetic data have been successfully analyzed according to the isotropic Heisenberg model for linear chains.The α forms exhibit antiferromagnetic behaviour with J values of -25, -29, and -29 cm-1 for the octyl, decyl, and dodecyl derivatives respectively.The β forms are ferromagnetic and have corresponding J values of 1.8, 2.1, and 2.3 cm-1 respectively.Magneto-structural correlations in these extended chain coordination polymers are discussed.
