75080-14-7

Usage

Family

Benzimidazoles
A group of chemical compounds to which MBT belongs

Usage

Rubber vulcanization accelerator and antioxidant
Common applications in the manufacturing of rubber products

Products

Tires, belts, and hoses
Examples of rubber products that may use MBT in their production

Function

Improves physical properties and stability of rubber compounds
MBT enhances the strength, elasticity, and durability of rubber products by promoting crosslinking of polymer chains during vulcanization

Caution

Potential toxicity and health hazards
MBT may pose risks to human health and the environment

Safety measures

Proper handling and usage required
Necessary precautions to be taken when working with MBT to minimize exposure and potential hazards

Upstream product

• 134469-07-1 Benzimidazol-2-thiol 
• 87504-17-4 2-cyclohexylbenzimidazo<1,2-d><1,2,4>thiadiazol-3(2H)-one 
• 85997-29-1 2-butylbenzimidazo<1,2-d><1,2,4>thiadiazol-3(2H)-one 
• 98154-63-3 2-ethyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one 
• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 72885-92-8 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one 

Relevant academic research and scientific papers

Synthesis and preliminary evaluation of benzimidazole derivatives as antimicrobial agents

A series of 2-alkylsulphanylbenzimidazoles was synthesised and the compounds were evaluated for their in vitro antimicrobial activity. The structures of the compounds were confirmed by 1H-NMR and IR data, and their purity by elemental analysis. Antimycobacterial activities against Mycobacterium tuberculosis and non-tuberculous mycobacteria as well as antifungal activities against Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Trichosporon beigelii, Trichophyton mentagrophytes and Aspergillus fumigatus were expressed as the corresponding MIC values. The substances exhibited appreciable antimycobacterial activity, in particular, against non-tuberculous mycobacteria. The activity of the most active compound in the set, 3,5-dinitro derivative 4t, exceeded that of the standard isoniazide against M. kansasii and M. avium. The antifungal activities of the compounds were relatively low. A weak antifungal effect was observed against the dermatophyte Trichophyton mentagrophytes. None of the compounds showed significant inhibitory activity against yeasts.

Fission of 1,2,4-Thiadiazol-3-ones by Triphenylphosphane: Triphenylphosphonio Thioimidazolates and Their Consecutive Reactions

Treatment of benzimidazothiadiazol-3(2H)-ones (1) and imidazothiadiazol-3(2H)-ones (17) with triphenylphosphan leads to the liberation of isocyanate and the formation of triphenylphosphonio-thiobenzimidazolat (4) and triphenylphosphonio-thioimidazolat (18), respectively. 2,4-Diphenyl-5-phenylimino-1,2,4-thiadiazol-3-one (23) is desulfurized with Ph3P and decomposed into phenyl isocyanate and diphenylcarbodiimide whereas the N-unsubstituted imino-thiadiazol-3-one (25) is attacked at the exocyclic imino group by Ph3P to give the N-phosphoranylidene thiourea (26).The structure of 4 can be rationalized as a dynamic system between polar and apolar valence isomeres.Reactions of 1 and 17 with cyanates, isocyanates, carbon disulfide, acetic anhydride, amines, benzyl chloride, grignard compounds, and CH acidic compounds are described.