87504-17-4

Upstream product

• 1155-37-9 bis-benzimidazole disulfide 
• 3173-53-3 Cyclohexyl isocyanate 
• 85997-29-1 2-butylbenzimidazo<1,2-d><1,2,4>thiadiazol-3(2H)-one 
• 538-75-0 dicyclohexyl-carbodiimide 
• 21928-74-5 2-thioxo-2,3-dihydro-benzoimidazole-1-carboxylic acid cyclohexylamide 

Downstream Products

• 68406-57-5 N-cyclohexylbenzimidazol-2-ylsulphenamide 
• 51314-51-3 N-butyl-1H-benzo[d]imidazol-2-amine 
• 118795-48-5 1-(3-Methyl-benzo[4,5]imidazo[2,1-b]thiazol-2-yl)-ethanone; compound with 1,3-dihydro-benzoimidazole-2-thione 
• 83792-76-1 (1H-benzoimidazol-2-yl)-(cyclohexyl)-amine 
• 51290-77-8 2-(benzylthio)-1H-benzo[d]imidazole 
• 2360-29-4 2-(phenylsulfanyl)-1H-benzimidazole 
• 75080-14-7 2-isobutylmercapto-1H-benzimidazole 
• 98154-69-9 2-(1-Cyclohexylcarbamoyl-1H-benzoimidazol-2-ylsulfanyl)-malonic acid diethyl ester 
• 98183-15-4 2-(1-Acetyl-2-oxo-propylsulfanyl)-benzoimidazole-1-carboxylic acid cyclohexylamide 
• 41066-67-5 N-phenylbenzimidazol-2-ylsulphenamide 
• 72885-89-3 3-phenylimino-3H-benzimidazo<2,1-c><1,2,4>-dithiazole 
• 98154-79-1 2-(4-Nitro-phenyl)-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one 
• 98154-68-8 2-(1-Cyclohexylcarbamoyl-1H-benzoimidazol-2-ylsulfanyl)-3-oxo-butyric acid ethyl ester 
• 98154-74-6 ethyl α-(1-cyclohexylcarbamoylbenzimidazol-2-ylthio)acetate 

Relevant academic research and scientific papers

Exchange, Elimination, and Ring Opening Reactions of 2,3-Dihydrobenzimidazothiadiazoles and 3H-Benzimidazodithiazoles

The reactions of benzimidazothiadiazol-3(2H)-ones (1) with isocyanates, isothiocyanates, carbon disulphide, aryl cyanates, acetylenedicarboxylates, and enamines, with exchange of the isocyanate component of (1), to give the corresponding condensed benzimidazole derivatives (1)-(6) are described.Under more severe conditions the 1-benzothiazol-2-yl-1,3-dihydrobenzimidazole-2-thiones (7) were obtained from aromatic isothiocyanates.Thermolysis of the thiadiazoles (1) led to the triazine derivative (12) with elimination of isocyanate and sulphur, and in the presence of phenols to the 2-aryloxybenzimidazoles (13).With amines and CH-acidic compounds, the S,N bond in compound (1) was cleaved to give benzimidazol-2-ylsulphenamides (14), and the ω-substituted methylthiobenzimidazoles (17) and (18).With cyanide ion, insertion into the S,N bond of compound (1) to furnish the thiadiazine (22) took place.The dithiazoles (2) were fragmented by amines to give 1,3-dihydrobenzimidazole-2-thione and guanidine with loss of sulphur; reaction with cyanide ion then gave the dibenzimidazothiadiazine (25).

ACYLIERUNG VON HETEROCYCLEN MIT KOHLENSAEUREDERIVATEN-III; SYNTHESEN VON BENZIMIDAZOLO (1,2,4)THIADIAZOLINEN

The addition products of benzimidazolinethione and isocyanates are easily cyclized to benzimidazolo(1,2,4)thiadiazoline systems 4 by treatment with Br2/NEt3.The thio-analogues 9 were synthesized from 2-aminophenyl thioureas and thiophosgene followe