75092-01-2

Basic information

• Product Name: 4-trifluoromethylcyclohexanone oxime
• Synonyms: 4-trifluoromethylcyclohexanone oxime
• CAS NO: 75092-01-2
• Molecular Weight: 181.158
• Mol File: 75092-01-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-trifluoromethylcyclohexanone oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 4-trifluoromethylcyclohexanone oxime(75092-01-2)
• EPA Substance Registry System: 4-trifluoromethylcyclohexanone oxime(75092-01-2)

Safety Data

• Hazardous Substances Data: 75092-01-2(Hazardous Substances Data)

Upstream product

• 75091-99-5 4-(trifluoromethyl)cyclohexan-1-one 
• 343217-50-5 Trifluoro-acetic acid 4-trifluoromethyl-cyclohexyl ester 
• 75091-92-8 4-(trifluoromethyl)cyclohexan-1-ol 

Downstream Products

• 1073266-02-0 trans-4-(trifluoromethyl)cyclohexane-1-amine 
• 1073266-01-9 cis-4-(trifluoromethyl)cyclohexanamine 
• 455-14-1 4-trifluoromethylphenylamine 

Relevant articles and documents

Aliphatic C-H Bond Oxidation with Hydrogen Peroxide Catalyzed by Manganese Complexes: Directing Selectivity through Torsional Effects

Substituted N-cyclohexyl amides undergo aliphatic C-H bond oxidation with H2O2 catalyzed by manganese complexes. The reactions are directed by torsional effects leading to site-selective oxidation of cis-1,4-, trans-1,3-, and cis-1,2-cyclohexanediamides. The corresponding diastereoisomers are unreactive under the same conditions. Competitive oxidation of cis-trans mixtures of 4-substituted N-cyclohexylamides leads to quantitative conversion of the cis-isomers, allowing isolation and successive conversion of the trans-isomers into densely functionalized oxidation products with excellent site selectivity and good enantioselectivity.