7510-62-5

Usage

Uses

Used in Organic Synthesis:
2-(biphenyl-4-yl)-2-oxoethyl 2,2-dimethylpropanoate is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure allows it to be a versatile component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(biphenyl-4-yl)-2-oxoethyl 2,2-dimethylpropanoate is used as an intermediate in the synthesis of drug molecules. Its presence in the molecular structure can contribute to the development of new medications with specific therapeutic properties.
Used in Agrochemical Industry:
2-(biphenyl-4-yl)-2-oxoethyl 2,2-dimethylpropanoate is also utilized in the agrochemical industry as a precursor for the development of pesticides and other crop protection agents. Its role in these applications is to provide a structural foundation for the creation of effective and targeted agrochemicals.
Used in Specialty Chemicals Industry:
In the specialty chemicals industry, 2-(biphenyl-4-yl)-2-oxoethyl 2,2-dimethylpropanoate is employed as a key component in the synthesis of various specialty chemicals. These can include dyes, fragrances, and other high-value compounds that require precise molecular structures for their intended applications.

Upstream product

• 75-98-9 Trimethylacetic acid 
• 37166-61-3 1-([1,1′-biphenyl]-4-yl)-2-hydroxyethanone 
• 3282-30-2 pivaloyl chloride 
• 92-91-1 biphenyl-4-acetaldehyde 
• 135-73-9 2-Bromo-4'-phenylacetophenone 

Downstream Products

• 92-91-1 biphenyl-4-acetaldehyde 
• 2001-23-2 1-(biphenyl-4-yl)-2-phenylethanone 

Relevant academic research and scientific papers

Palladium-Catalyzed Chemo- and Enantioselective C?O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis

A chemoselective C?O bond cleavage of the ester alkyl side-chain of α-acyloxy ketones was realized for the first time by a highly efficient palladium-catalyzed hydrogenolysis (S/C=6000, the highest catalytic efficiency by far). Furthermore, a kinetic resolution of α-acyloxy ketones was first developed by enantioselective hydrogenolysis with good yields and up to 99 % ee.

Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1- arylethanones

First hand: The first example of a palladium-catalyzed asymmetric hydrogenation of α-acyloxy ketones (1) was accomplished to give the hydrogenated products 2 with by far the highest catalytic efficiency in up to quantitative conversions and excellent enantioselectivities. The hydrogenated products could serve as important intermediates for the preparation of many drug candidates. TFE=2,2,2-trifluoroethanol. Copyright

Arylation of α-pivaloxyl ketones with arylboronic reagents via Ni-catalyzed sp3 C-O activation

A Suzuki-Miyaura coupling of α-pivaloxyl ketones via Ni-catalyzed sp3 C-O activation to produce α-aryl ketones is developed. This study offers a convenient method to construct α-arylation products from readily available α-hydroxyl carbonyl compounds.