75102-03-3Relevant academic research and scientific papers
A general route to α-alkyl (E)-α,β-unsaturated aldehydes
Lahmar, Nour,Aatar, Jamaa,Ayed, Ta?cir Ben,Amri, Hassen,Bellassoued, Moncef
, p. 3018 - 3026 (2007/10/03)
Bis(trimethylsilyl)-tert-butylaldimines 3 react with aldehydes in the presence of zinc bromide at room temperature to give, after hydrolysis, the desired α-alkyl α,β-ethylenic aldehydes in good yield and with very high E stereoselectivity. The reaction was believed to proceed via the α-silyl β-siloxyimines 4.
PHOSPHONATES α-LITHIES AGENTS DE TRANSFERT FONCTIONNEL. PREPARATION D'ALDEHYDES α,β-INSATURES α-SUBSTITUES.
Tay, M. K.,Aboujaoude, E. E.,Collignon, N.,Savignac, Ph.
, p. 1263 - 1266 (2007/10/02)
Condensation of α-lithioalkylphosphonates with ethoxymethyleneaniline leads to lithiated enaminoalkylphosphonates directly convertible on reaction with aldehydes into α,β-unsaturated α-substituted aldehydes.
