75104-95-9Relevant articles and documents
DMSO-mediated palladium-catalyzed cyclization of two isothiocyanates: Via C-H sulfurization: A new route to 2-aminobenzothiazoles
Yao, Guangkai,Wang, Bing-Feng,Yang, Shuai,Zhang, Zhi-Xiang,Xu, Han-Hong,Tang, Ri-Yuan
, p. 3403 - 3406 (2019/02/10)
DMSO was found to activate arylisothiocyanates for self-nucleophilic addition. A subsequent intramolecular C-H sulfurization catalyzed by PdBr2 enables access to a wide range of 2-aminobenzothiazole derivatives in moderate to good yields. This is the first example of a DMSO-mediated Pd-catalyzed synthesis of 2-aminobenzothiazoles through cyclization/C-H sulfurization of two isothiocyanates.