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Minoxidil IMpurity D, also known as 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide, is an intermediate compound used in the synthesis of Minoxidil (M354000), a medication primarily used for the treatment of high blood pressure and hair loss. It plays a crucial role in the pharmaceutical industry due to its involvement in the production process of a widely prescribed drug.

75105-16-7

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75105-16-7 Usage

Uses

Used in Pharmaceutical Industry:
Minoxidil IMpurity D is used as an intermediate in the preparation of Minoxidil (M354000) for the treatment of high blood pressure and hair loss. Its presence in the synthesis process is essential for the development of the final drug product, which has proven to be effective in managing these medical conditions.
Minoxidil IMpurity D is also used as a hypotensive agent, contributing to the development of medications that help lower blood pressure and reduce the risk of cardiovascular diseases. Its role in the pharmaceutical industry is significant, as it aids in the production of life-saving drugs that improve the quality of life for many patients.

Check Digit Verification of cas no

The CAS Registry Mumber 75105-16-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,0 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 75105-16:
(7*7)+(6*5)+(5*1)+(4*0)+(3*5)+(2*1)+(1*6)=107
107 % 10 = 7
So 75105-16-7 is a valid CAS Registry Number.

75105-16-7Upstream product

75105-16-7Downstream Products

75105-16-7Relevant academic research and scientific papers

Method for the preparation of a therapeutically active compound

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, (2008/06/13)

A method for the preparation of 2,4-diamino-3-oxy-6-piperidyl-pyrimidine or minoxidil wherein a compound of the formula STR1 wherein R is a C1-4 alkyl or a phenyl group optionally having up to three C1-4 alkyl substituents, is oxidized to a compound of the formula STR2 which according to known methods is reacted with piperidine to minoxidil. In the inventive method magnesium monoperoxyphthalate, which has the formula STR3 is used as the oxidizing agent.

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