75107-16-3

Upstream product

• 2052-01-9 2-bromo-2-methylpropionic acid 
• 100-51-6 benzyl alcohol 
• 20769-85-1 2-bromoisobutyric acid bromide 

Downstream Products

• 160115-34-4 benzyl 2,2-dimethyl-3-oxobutanoate 
• 2495-37-6 benzyl methacrylate 
• 1257264-48-4 Benzyl 2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoate 
• 1447942-68-8 benzyl 2-methyl-2-(tetrahydro-2H-pyran-2-yl)propanoate 
• 1447943-93-2 C₁₇H₂₅NO₃ 
• 1447942-60-0 benzyl 2-(4,4-difluoropiperidin-1-yl)-2-methylpropanoate 
• 1610949-90-0 C₁₇H₂₃NO₄ 
• 1610949-91-1 C₁₈H₂₆N₂O₅ 
• 1610949-87-5 C₁₄H₁₉NO₄ 

Relevant academic research and scientific papers

Multifunctional linear methacrylate copolymer polyenes having pendant vinyl groups: Synthesis and photoinduced thiol-ene crosslinking polyaddition

UV-induced thiol-ene crosslinked films composed of linear methacrylate copolymers having pendant enes (MCPenes) are reported. An approach involving a combination of controlled radical polymerization to synthesize well-controlled pendant hydroxyl containing copolymers (MCPOHs) with the following facile carbodiimide coupling of the formed MCPOHs with enes allows for the synthesis of well-controlled MCPenes with narrow molecular weight distribution. The density of the pendant enes in MCPenes are easily modulated by varying monomer ratios in the feed. Under UV irradiation, the resulting MCPenes undergo thiol-ene polyaddition reactions with polythiols to form crosslinked films with a uniform network. The results from thermal and mechanical analysis suggest these properties are tuned by adjusting the densities of pendant enes in MCPenes and the amount of thiols in the reactive mixtures.

Single-ion diblock copolymers for solid-state polymer electrolytes

Li-ion battery technology is considered as the most efficient solution for the electrochemical energy storage. While standard liquid electrolyte - based configurations provide best performances, solid state electrolytes are developed as a safer alternative. Herein, we discuss a three step synthesis procedure of self-doped solid block copolymer electrolyte, combining a single-ion poly(lithium methacrylate-co-oligoethylene glycol methacrylate) ion conducting block (P(MALi-co-OEGMA)) and a structuring polystyrene block (PS). The macromolecular design allows the formation of a self-standing film with excellent mechanical properties provided by the PS anchoring nanodomains while attaining attractive ionic conductivities of up to 0.02 mS/cm at room temperature. Moreover, the single-ion configuration based on polyanionic backbone affords high transference numbers, close to unity, and alleviates the power limitation encountered in salt-doped solid polymer electrolyte (SPE). The electrolyte exhibits a wide electrochemical stability window up to 4.5 V vs. Li+/Li and promote the formation of stable interfaces at the electrodes.

Access to α-Cyano Carbonyls Bearing a Quaternary Carbon Center by Reductive Cyanation

Reductive cyanation of tertiary alkyl bromides using electrophilic cyanating reagent and zinc reductant was developed, providing various α-cyano ketones, esters, and carboxamides containing a nitrile-bearing all-carbon quaternary center in good to excellent yields under mild reaction conditions. The corresponding reaction mechanism involving in situ generated organozinc reagent and reactivity distinction was elucidated by density functional theory computation.

CYCLIC TRIPEPTIDE MIMETICS AS PLASMIN INHIBITORS

The invention relates to peptide mimetics comprising the residues P4-P3-P2-P1, which were cyclized between the side chains of P3 and P2 amino acid and are, as inhibitors of the serine protease plasmin, suitable to be used to inhibit fibrinolysis and thus to reduce blood loss in hyperfibrinolytic conditions, for example during surgery.

Utilising 14C-radiolabelled atom transfer radical polymerisation initiators

14C-radio-initiated atom transfer radical polymerisations allow direct monitoring of the fate of initiating species.

PIPERIDINE DERIVATIVE AND USE THEREOF

The present invention provides a novel piperidine derivative and a tachykinin receptor antagonist containing same, as well as a compound represented by the formula:wherein R1 is carbamoylmethyl, methylsulfonylethylcarbonyl and the like; R2 is methyl or cyclopropyl; R3 is a hydrogen atom or methyl; R4 is a chlorine atom or trifluoromethyl; R5 is a chlorine atom or trifluoromethyl; and a group represented by the formula:is a group represented by the formula:wherein R6 is a hydrogen atom, methyl, ethyl or isopropyl; R7 is a hydrogen atom, methyl or a chlorine atom; and R8 is a hydrogen atom, a fluorine atom, a chlorine atom or methyl; or 3-methylthiophen-2-yl, and a salt thereof.

Structure-LCST relationships for end-functionalized water-soluble polymers: An "accelerated" approach to phase behaviour studies

A novel "high throughput" technique for LCST measurement was developed which is able to identify the effect of subtle changes in end group composition on the aqueous phase behaviour of water-soluble poly(2- (dimethylamino)ethyl methacrylate). The Royal Society of Chemistry.

Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers

The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).