7511-27-5

Basic information

• Product Name: 1-bromo-7-methylnaphthalene
• CAS NO: 7511-27-5
• Molecular Formula: C₁₁H₉Br
• Molecular Weight: 221.0932
• Mol File: 7511-27-5.mol

Chemical Properties

• Boiling Point: 301.2°C at 760 mmHg
• Flash Point: 137.6°C
• Density: 1.417g/cm³
• Vapor Pressure: 0.00191mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 1-bromo-7-methylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-7-methylnaphthalene(7511-27-5)
• EPA Substance Registry System: 1-bromo-7-methylnaphthalene(7511-27-5)

Safety Data

• Hazardous Substances Data: 7511-27-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-bromo-7-methylnaphthalene is used as a reagent in organic synthesis for the preparation of various substituted naphthalene derivatives. Its bromine atom allows for the formation of carbon-carbon and carbon-heteroatom bonds, making it a valuable intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-bromo-7-methylnaphthalene is utilized as a key building block in the synthesis of various medicinal compounds. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
1-bromo-7-methylnaphthalene is employed in the agrochemical sector for the synthesis of pesticides and other crop protection agents. Its chemical properties enable the creation of effective and targeted agrochemicals to enhance crop yield and protect against pests.
Used in Dye Production:
In the dye industry, 1-bromo-7-methylnaphthalene serves as a precursor for the synthesis of various dyes and pigments. Its bromine atom and naphthalene structure contribute to the color and stability of the resulting dyes, making it a valuable component in the production of high-quality dyes.
However, it is important to handle 1-bromo-7-methylnaphthalene with caution due to its potential health hazards and environmental impact. Proper safety measures should be taken to minimize risks during its use in various applications.

Upstream product

• 76-84-6 triphenylmethyl alcohol 
• 127810-66-6 8-bromo-2-hydroxy-2-methyl-1,2,3,4-tetrahydronaphthalene 
• 412041-50-0 1,2-diethynyl-4-methylbenzene 

Downstream Products

• 38879-97-9 7-methylnaphthalene-1-carbonitrile 
• 98331-27-2 8-bromo-2-(bromomethyl)naphthalene 
• 35387-22-5 7-Methyl-[1]naphthoesaeure 
• 841259-41-4 8-bromonaphthalene-2-carbaldehyde 
• 135942-96-0 1-cyano-7-(bromomethyl)naphthalene 
• 98331-29-4 7-Bromomethyl-1-(3-bromomethyl-phenoxy)-naphthalene 
• 98331-28-3 7-Methoxymethyl-1-(3-methoxymethyl-phenoxy)-naphthalene 

Relevant articles and documents

Regioselective haloaromatization of 1,2-bis(ethynyl)benzene via halogen acids and PtCl2. Platinum-catalyzed 6-π electrocyclization of 1,2-bis(1′-haloethenyl)benzene intermediates

Treatment of 1,2-bis(ethynyl)benzene (1) with aqueous HX (X = Br, I) in hot 3-pentanone (100-105 °C, 2 h) afforded 1,2-bis(1′-haloethenyl)benzene species 2-Br and 2-I in 98% and 95% yields, respectively. The hydrochlorination of endiyne 1 failed to proceed at elevated temperature but was implemented efficiently by PtCl2 (5 mol %) in hot 3-pentanone (100 °C, 2 h) to give 1,2-bis(1′-chloroetheny)benzene 2-Cl in 80% yield. In the presence of PtCl2 (5 mol %), these halides 2-Cl, 2-Br, and 2-I were subsequently converted to 1-halonaphthalenes 3-Cl, 3-Br, and 3-I in the mother solution via sequential 6-π electrocyclization and dehalogenation reactions. PtCl2 (5 mol %) also effected direct haloaromatization of endiyne 1 with HX (X = Cl, Br, I) and gave 1-halonaphthalenes 3-Cl, 3-Br, and 3-I in 64-71% yields. This investigation reports the scope and the regioselectivity of haloaromatization of various enediynes catalyzed by PtCl2.

Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents

This invention relates to novel [(substituted naphthalenyl)alkyl]-3H-1,2,3,5-oxathiadiazole 2-oxides, to the processes for their preparation, to methods for using the compounds, and to pharmaceutical compositions thereof. The compounds have pharmaceutical

Processes for the preparation of novel naphthalenylmethyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents

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