38879-97-9

Usage

Uses

Used in Organic Synthesis:
1-Cyano-7-methylnaphthalene is used as a building block for the synthesis of various chemical compounds, contributing to the development of new materials and products in the chemical industry.
Used in Research and Development:
1-Cyano-7-methylnaphthalene is employed as a research compound for exploring its unique chemical properties and reactivity, which can lead to advancements in the understanding of organic chemistry and the creation of novel applications.

Upstream product

• 7511-27-5 1-bromo-7-methylnaphthalene 
• 544-92-3 copper(I) cyanide 
• 117294-21-0 8-bromo-2-tetralone 
• 127810-66-6 8-bromo-2-hydroxy-2-methyl-1,2,3,4-tetrahydronaphthalene 
• 55116-09-1 2-bromophenylacetyl chloride 
• 18698-97-0 ortho-bromophenylacetic acid 
• 22009-37-6 7-methyl-3,4-dihydro-2H-naphthalen-1-one 
• 162150-56-3 3,4-dihydro-7-methylnaphthalene-1-carbonitrile 
• 151-50-8 potassium cyanide 

Downstream Products

• 63409-06-3 7-methyl-1-naphthalenecarboxaldehyde 
• 162150-57-4 7-naphthaldehyde-1-carbonitrile 
• 35387-22-5 7-Methyl-[1]naphthoesaeure 
• 135942-96-0 1-cyano-7-(bromomethyl)naphthalene 

Relevant academic research and scientific papers

Synthesis of 8,8′-Disubstituted 1,1′-Binaphthyls Stable to Atropisomerization: 2,2′-Dimethyl-1,1′-binaphthalene-8,8′-diol and 2,2′-Dimethyl-8,8′-bis(4-tert-butyloxazolyl)-1,1′-binaphthyl

Axially chiral binaphthyls 3a and 3b were synthesized taking, advantage of Ullman coupling of 4a and 4b, respectively. The binaphthyls were shown to be stable to atropisomerization. Binaphthol 3b was resolved with (-)-(1S)-menthyl chloroformate (11). R-axis diastereomer of bisoxazoline 3b was used for enantioselective cyclopropanation of styrene with ethyl diazoacetate.

A CONVENIENT ACCESS TO 1,7-DIFUNCTIONAL NAPHTHALENES : THE SYNTHESIS OF THE 1,7-DICARBALDEHYDE 7-MONODIMETHYLACETAL

An easily accessible route to the 1,7-dicarbaldehyde 7-monodimethylacetal 7 is described.It proceeds in a six step sequence from the known 7-methyl-1-tetralone.

Antihyperglycemic Activity of Novel Naphthalenyl 3H-1,2,3,5-Oxathiadiazole 2-Oxides

A series of naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxides was prepared and tested for antihyperglycemic activity in the db/db mouse, a model for type 2 (non-insulin dependent) diabetes mellitus.Substitution at the 1-,5-, or 8-positions of the naphthalene ring with a halogen was found to be beneficial to antihyperglycemic activity. 4--3H-1,2,3,5-oxathiadiazole 2-oxide (45), one of the most potent compounds in this series, was selected for further pharmacological evaluation.