75120-94-4Relevant academic research and scientific papers
Heteroatom-embedded medium-sized cycloalkynes: Concise synthesis, structural analysis, and reactions
Ni, Runyan,Mitsuda, Naoto,Kashiwagi, Takeru,Igawa, Kazunobu,Tomooka, Katsuhiko
, p. 1190 - 1194 (2015)
A variety of medium-sized cycloalkynes were efficiently synthesized by the double Nicholas reaction of cobalt complex and bis(hetero)substituted acyclic compound. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Furthermore, preparation of multifunctionalized alkynes was achieved by embedding the cycloalkyne within a peptide chain.
N,N'-Doacylated imidazolidines and hexahydropyrimidines
Luk'yanov, O. A.,Pokhvisneva, G. V.,Ternikova, T. V.
, p. 1376 - 1380 (2007/10/02)
A method for the preparation of N-monoacyl imidazolidines and hexahydropyrimidines (as hydrochlorides) by interaction of monoacylated derivatives of ethylenediamine and trimethylethylenediamine with chloromethyl methyl ether was developed.Also a method for the preparation of N,N'-diacylimidazolidines and hexahydropyrimidines either by acylation of their monoacyl derivatives or by reaction of the corresponding N,N'-diacyl alkylenediamine derivatives with dimethoxymethane, diacetoxymethane, 1,3,5-trioxane or chloromethyl methyl ether was designed. - Key words: N-mono- and N,N'-diacylated imidazolidines, N-mono- and N,N'-diacylated hexahydropyrimidines, N,N'-diacylated alkylenediamines, acylation, methylation, cyclization.
Dynamic Protection of Amines using 18-Crown-6
Barrett, Anthony G. M.,Lana, J. Carlos A.,Tograie, Shahrzad
, p. 300 - 301 (2007/10/02)
The regioselectivity of diamine monoacylation has been controlled by selective complexation with 18-crown-6 and a proton source.
