75150-23-1

Usage

InChI:InChI=1/C11H22N2O/c1-9(2)10(14)12-7-11(3,4)8-13(5)6/h1,7-8H2,2-6H3,(H,12,14)

Upstream product

• 53369-71-4 N,N,2,2-tetramethyl-1,3-propanediamine 
• 86119-84-8 phosphoric acid 
• 97-88-1 2-methyl-butyl acrylate 

Downstream Products

• 110613-72-4 N-<2,2-dimethyl-3-(N,N-dimethylamino)propyl>-5-<<(tert-butyloxy)carbonyl>amino>-6-cyclohexyl-4-hydroxyhex-1-ene-2-carboxamide 
• 110613-49-5 ((S)-1-{(S)-1-[(S)-1-Cyclohexylmethyl-4-(3-dimethylamino-2,2-dimethyl-propylcarbamoyl)-2-hydroxy-pent-4-enylcarbamoyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester 
• 110613-47-3 {(S)-1-[(S)-1-[(S)-1-Cyclohexylmethyl-4-(3-dimethylamino-2,2-dimethyl-propylcarbamoyl)-2-hydroxy-pent-4-enylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester 
• 110613-48-4 ((S)-1-{(S)-1-[(S)-1-Cyclohexylmethyl-4-(3-dimethylamino-2,2-dimethyl-propylcarbamoyl)-2-hydroxy-pent-4-enylcarbamoyl]-2-phenyl-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 110613-41-7 ((S)-1-{(S)-1-[(S)-1-Cyclohexylmethyl-4-(3-dimethylamino-2,2-dimethyl-propylcarbamoyl)-2-hydroxy-pent-4-enylcarbamoyl]-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 118233-42-4 (S)-5-Amino-6-cyclohexyl-4-hydroxy-2-methylene-hexanoic acid (3-dimethylamino-2,2-dimethyl-propyl)-amide; hydrochloride 

Relevant academic research and scientific papers

Process for preparation of α, β-unsaturated N-substituted-carboxylic acid amides

The invention relates to a process for the preparation of α, β-unsaturated N-substituted carboxylic acid amides, novel α, β-unsaturated N-substituted carboxylic acid amides, a process for the polymerization of these novel α, β-unsaturated N-substituted carboxylic acid amides, including the polymers, and the use of these polymers as sedimentation, flocculating, dewatering and retention aids, as additives for mineral oils, and as ion exchangers. The α, β-unsaturated N-substituted carboxylic acid amides are prepared by transamidation of β-hydroxy or β-alkoxy carboxylic acid amides with primary amines and heating of the N-substituted β-hydroxy or β-alkoxy carboxylic acid amides obtained as intermediate products in the vapor phase in the presence of catalysts. Primary amines are preferably used in the conversion which have no hydrogen beta to the amino group. These α,β-unsaturated carboxylic acid amides may be neutralized and/or quaternized and polymerized by processes which as such are known alone or with other comonomers, and preferably acrylic or methacrylic acid derivatives such as acrylamide, to give cationic polymers. These polymers are suited for use as flocculating and sedimentation aids, as dewatering and retention aids in papermaking, as additives for mineral oils, and as ion exchangers.

Preparation of carboxylic acid amides

What is disclosed is a method for making amides of the formula STR1 wherein R1 is hydrogen or methyl, R3 is straight-chain or branched alkyl or unsubstituted or substituted aryl, and R4 is hydrogen or straight-chain or branched unsubstituted or substituted alkyl, which comprises reacting an ester of the formula STR2 wherein R2 is alkyl having 1 to 6 carbon atoms, with heating and under autogenous pressure, in a homogeneous phase, with an amine of the formula STR3 said amine being present in an amount which is stoichiometrically deficient up to an amount which is in small stoichiometric excess with respect to said ester.