75160-54-2

Basic information

• Product Name: Thiourea, N-phenyl-N'-(2-pyridinylmethyl)-
• Synonyms: N-phenyl-N'-2-pyridinylmethylthiourea;HMS544N01
• CAS NO: 75160-54-2
• Molecular Formula: C13H13N3S
• Molecular Weight: 243.332
• Mol File: 75160-54-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Thiourea, N-phenyl-N'-(2-pyridinylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-phenyl-N'-(2-pyridinylmethyl)-(75160-54-2)
• EPA Substance Registry System: Thiourea, N-phenyl-N'-(2-pyridinylmethyl)-(75160-54-2)

Safety Data

• Hazardous Substances Data: 75160-54-2(Hazardous Substances Data)

Upstream product

• 3731-51-9 2-(Aminomethyl)pyridine 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 76259-03-5 (nitro-4 benzyl)thio-3 imidazo<1,5-a>pyridine 
• 76259-02-4 (chloro-4 benzyl)thio-3 imidazo<1,5-a>pyridine 
• 945734-44-1 [(phenyl-3-(2-methylpyridyl)-2-thioureate)diphenylphosphinesilver(I)] nitrate 
• 75160-64-4 3-phenylaminoimidazo<1,5-a>pyridine 
• 76259-00-2 dihydro-2,3 imidazo<1,5-a>pyridinethione-3 

Relevant articles and documents

Study of the sulfur atom as hydrogen bond acceptor in N(2)-pyridylmethyl- N′-arylthioureas

The hydrogen acceptor capability of the sulfur atom in the biologically relevant N-2-pyridylmethyl-N′-arilthioureas was explored. N-2-Pyridylmethyl thioreas were selected to avoid the formation of intramolecular six-membered hydrogen-bonded ring. The comp

(Thio)urea-catalyzed friedel-crafts reaction: Synthesis of bis(indolyl)-methanes

Bis(indolyl)methane derivatives (BIMs) were synthesized in moderate to good yields by (thio)urea catalyzed electrophilic substitution of indole (2) with various aldehydes 1. Reactions were performed under conventional and microwave (MW) heating, either using 1,2-dichloroetane as solvent or without solvent. The procedure using microwave heating was also applied to the synthesis of the natural products vibrindole A (3n), arsindoline A (3i), arundine (3o) and tris(1H-indol-3-yl)methane (3j). Additionally, the synthesis of streptindole was carried out via intermediate 3g. This methodology is well suited for the synthesis of bis(indolyl)methanes: it offers good yields of products, low sensitivity to moisture and oxygen, high tolerance to different functional groups on the aldehydes such as al-kynes and trimethylsilane, and simplicity in operation

Synthesis and crystal structure of N-phenyl-N′-(pyridin-2-ylmethyl)-S-methyl-thiouronium iodide

Methylation of N-phenyl-N′-(pyridin-2-ylmethyl)thiourea led to a new low melting thiouronium iodide salt, whereas a further methylation of the nitrogen of the pyridine ring was not successful. This could be explained by the inactivity of the nitrogen atom