75175-09-6

Upstream product

• 58574-03-1 4'-Hydroxybiphenyl-4-carboxylic acid 
• 26191-64-0 4'-methyl-biphenyl-4-ol 
• 108-24-7 acetic anhydride 
• 127783-74-8 4-acetoxy-4’-methylbiphenyl 
• 64-19-7 acetic acid 
• 94385-18-9 1,1-bis(4'-hydroxyphenyl)-4-methylcyclohexane 

Downstream Products

• 386750-30-7 4-cholesteryl 4'-acetoxybiphenyl carboxylate 
• 1632171-09-5 methyl 4-(spiro[chromene-2,4'-piperidin]-6-yl)benzoate 
• 1632171-08-4 methyl 4-(spiro[chromane-2,4'-piperidin]-6-yl)benzoate 
• 1632171-12-0 (4-(spiro[chromane-2,4'-piperidin]-6-yl)phenyl)methanol 
• 1632171-11-9 C₂₁H₂₃NO₃*ClH 
• 1632171-05-1 methyl 3'-acetyl-4'-hydroxy-[1,1'-biphenyl]-4-carboxylate 
• 1632171-06-2 tert-butyl 6-(4-(methoxycarbonyl)phenyl)-4-oxospiro[chromane-2,4'-piperidine]-1'-carboxylate 
• 1632171-07-3 tert-butyl 4-hydroxy-6-(4-(methoxycarbonyl)phenyl)spiro[chromane-2,4'-piperidine]-1'-carboxylate 

Relevant academic research and scientific papers

POLYMERIZABLE COMPOUND AND OPTICAL ANISOTROPIC BODY

PROBLEM TO BE SOLVED: To provide a polymerizable compound that prevents the occurrence of crystal deposition or the like when added to a polymerizable composition and has high storage stability. SOLUTION: This invention provides a compound represented by general formula (I), specifically, a compound of the following structure. This invention also provides a composition comprising the compound, a polymer obtained by polymerization of the composition and an optical anisotropic body using the polymer. COPYRIGHT: (C)2015,JPOandINPIT

A practical synthesis of (4-(spiro[chromane-2,4'-piperidin]- 6-yl)phenyl)methanol as a key intermediate of novel GPR119 agonist

Starting from commercially available 4'-hydroxy-[1,1'-biphenyl]- 4-carboxylic acid, a practical synthesis has been established in high yield for (4-(spiro[chromane-2,4'-piperidin]-6-yl)phenyl)methanol as a key intermediate for a novel GPR119 agonist.

Optically active compound and liquid crystal composition containing the compound

Optically active compounds of the following general formula (1) useful as chiral dopant, wherein n is an integer of 0 to 5, provided that when n is 0, A is a single bond (—) and that when n is 1 to 5, A is a single bond (—), —O—, —COO—, —Cy— or —Cy—COO— in which —Cy— is a trans-1,4-cyclohexylene group, each of X and Y is independently a hydrogen atom or a fluorine atom, B is a single bond (—), —COO—, —COO—Ph— or —Ph—COO— in which —Ph— is a 1,4-phenylene group, and C* is an asymmetric carbon. The chiral dopant of the present invention have a high helical twisting power of at least 9 and suitably have a feature that the helical pitch induced by them decreases in length with an increase in temperature so that they are advantageous for use in a nematic liquid crystal composition.

Chiral compounds as dopants for liquid crystals

An optically active compound of the general formula (1), ???wherein n is an integer of 4 to 8, X is -Ph-COO-Ph-Ph-, -Ph-Ph-COO-Ph-, -Ph-OOC-Ph-Ph-, -Ph-Ph-OOC-Ph-, -Ph-Ph-Ph-, -Cy-COO-Ph-Ph-, -Ph-Ph-OOC-Cy-, -Ph-OOC-Ph-COO-Ph-, -Ph-OOC-Cy-COO-Ph-, -Ph-OOC

A selective biomimetic tweezer for noradrenaline

The new highly preorganized tweezer molecule 1 binds noradrenaline in polar solvents with unprecedented specificity. It uses a biomimetic recognition pattern and rejects almost all other neurotransmitters. LB experiments on a film balance reflect the same

Optically active compound and liquid crystal composition containing the compound

An optically active compound of the following general formula (1) useful as a chiral dbpant, and use thereof, 1wherein each of X and Y is independently a hydrogen atom or a fluorine atom, R is (C2H5)2CHCH2C*H(CH

Optically active compound and liquid crystal composition containing the compound

An optically active compound of the general formula (1) useful as a chiral dopant and use thereof, wherein each of m and n is independently an integer of 4 to 8, A is —Ph—COO—Ph—, —Ph—Ph—COO—, —Cy—COO—Ph—, —Ph—OOC—Ph—COO—, —Ph—OOC—Cy—COO—, —Ph—OOC—Np—COO—

Thermal Properties of Pentaerythritol Derivatives with Chiral Moiety

Pentaerythritol derivatives containing four mesogenic groups with chiral moieties were synthesized. Cholesterol and 2-methyl-1-butanol were used as a chiral moiety. All compounds which derivative from pentaerythritol and mesogenic group showed a glass transition temperature above room temperature. Crystallization from melt of these compounds was strongly suppressed. The compound that the mesogenic group has one benzene ring linked by ester bonding between mesogenic and cholesteryl group exhibited the smectic A1 phase. While the compounds that the mesogenic group has two benzene rins linked by ester bonding with cholesteryl group exhibited the cholesteric phase. The compounds that the mesogenic group has three benzene rings linked by one ester bonding with 2-methylbutyl group also exhibited the smectic A2 phase and the cholesteric phase.

A Method for Preparing 4'-Hydroxybiphenyl-4-carboxylic Acid

4'-Hydroxybiphenyl-4-carboxylic acid was prepared by liquid-phase oxidation of 4'-alkoxy- and 4'-acetoxy-4-methylbiphenyl in acetic acid containing acetic anhydride in the presence of the ternary Co-Mn-ZrO catalyst promoted with NaBr.