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75175-77-8

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75175-77-8 Usage

Description

3-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL)-2-PROPEN-1-ONE, also known as 4-fluoro PVP, is a synthetic chemical compound that is a derivative of the stimulant drug alpha-PVP. It is classified as a cathinone and is known for its stimulant and psychoactive effects, which can produce feelings of euphoria, increased energy, and heightened alertness. However, it has a high potential for abuse and addiction, leading to legal restrictions in many countries.

Uses

Used in Pharmaceutical Research:
3-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL)-2-PROPEN-1-ONE is used as a research chemical for studying the effects and mechanisms of action of stimulant drugs. Its structural and functional similarities to other cathinones make it a valuable tool in understanding the pharmacology of these substances.
Used in Forensic Analysis:
In the field of forensic analysis, 3-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL)-2-PROPEN-1-ONE is used for the identification and analysis of designer drugs. Its detection in seized materials can provide valuable information about the presence of controlled substances and their distribution.
Used in Controlled Substance Regulation:
Due to its high potential for abuse and addiction, 3-(DIMETHYLAMINO)-1-(4-FLUOROPHENYL)-2-PROPEN-1-ONE is subject to legal restrictions and is regulated as a controlled substance in many countries. Its production, sale, and possession are monitored and controlled to prevent misuse and protect public health.

Check Digit Verification of cas no

The CAS Registry Mumber 75175-77-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,7 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 75175-77:
(7*7)+(6*5)+(5*1)+(4*7)+(3*5)+(2*7)+(1*7)=148
148 % 10 = 8
So 75175-77-8 is a valid CAS Registry Number.

75175-77-8 Well-known Company Product Price

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  • Alfa Aesar

  • (H34021)  3-Dimethylamino-1-(4-fluorophenyl)-2-propen-1-one, 97%   

  • 75175-77-8

  • 5g

  • 337.0CNY

  • Detail
  • Alfa Aesar

  • (H34021)  3-Dimethylamino-1-(4-fluorophenyl)-2-propen-1-one, 97%   

  • 75175-77-8

  • 25g

  • 1127.0CNY

  • Detail

75175-77-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(dimethylamino)-1-(4-fluorophenyl)prop-2-en-1-one

1.2 Other means of identification

Product number -
Other names 3-dimethylamino-1-(4-fluoro-phenyl)-propenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75175-77-8 SDS

75175-77-8Relevant articles and documents

Access to α,α-dihaloacetophenones through anodic C[dbnd]C bond cleavage in enaminones

Zhang, Zhenlei,Yang, Jiusi,Wu, Kairui,Yu, Renjie,Bu, Jiping,Huang, Zijun,Li, Shaoke,Ma, Xiantao

supporting information, (2021/12/20)

We have developed a method to synthesize α,α-dihaloketones under electrochemical conditions. In this reaction, the Cl- or Br- is oxidized to Cl2 or Br2 at the anode, which undergoes two-step addition reactions with the N,N-dimethyl enaminone, and finally breaks C[dbnd]C of the N,N-dimethyl enaminone to generate α,α-dihaloketones. The electrosynthesis reaction can be conveniently carried out in an undivided electrolytic cell at room temperature. In addition, various functional groups are compatible with this green protocol which can be applied simultaneously to the gram scale without significantly lower yield.

SUBSTITUTED ARYL COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF

-

Paragraph 0223-0224, (2021/11/04)

The present application relates to a substituted aryl compound or a pharmaceutically acceptable salt, a stereoisomer, a polymorph, a solvate, a N-oxide, an isotope-labeled compound, a metabolite or a prodrug thereof, and a preparation method therefor and use thereof, also relates to a pharmaceutical composition containing the compound and a therapeutic use thereof. The compound or a pharmaceutical composition thereof can inhibit the activity of adenosine A2a receptor, and can be used for treating or preventing a disease related to adenosine A2a receptor, especially for treating a tumor.

An expedient synthesis of highly functionalized 1,3-dienes by employing cyclopropenes asC4units

Jiang, Chengzhou,Wu, Jiamin,Han, Jiabin,Chen, Kai,Qian, Yang,Zhang, Zhengyu,Jiang, Yaojia

supporting information, p. 5710 - 5713 (2021/06/16)

An efficient method has been described to synthesize dicarbonyl functionalized 1,3-dienes by cleaving the CC bond of enaminones with cyclopropenes in the presence of a rhodium catalyst. The acetate-substituted cyclopropenes are judiciously chosen as standardC4units of 1,3-diene precursors. The reactions are believed to undergo a unique cutting and insertion process, involving a CC bond cleavage of the enaminone and insertion of a newC(sp2) source with the formation of two C-C single bonds. A broad range of substrates can be used to synthesize the corresponding 1,3-dienes under very mild reaction conditions, including low catalyst-loading, ambient temperature, and a neutral reaction solvent.

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