914635-88-4

Usage

Uses

Used in Pharmaceutical Industry:
1-(6-(4-FLUOROPHENYL)-2-METHYLPYRIDIN-3-YL)ETHANONE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(6-(4-FLUOROPHENYL)-2-METHYLPYRIDIN-3-YL)ETHANONE is used as a building block for the creation of novel agrochemicals, such as pesticides and herbicides, that can help improve crop protection and yield.
Used in Materials Science:
1-(6-(4-FLUOROPHENYL)-2-METHYLPYRIDIN-3-YL)ETHANONE is utilized as a component in the development of advanced materials with specific properties, such as improved conductivity, stability, or reactivity, for use in various applications, including electronics, coatings, and composites.

Upstream product

• 50-00-0 formaldehyd 
• 896885-34-0 1-(4-fluorophenyl)ethan-1-one-O-acetyl oxime 
• 123-54-6 acetylacetone 
• 1118-66-7 4-amino-3-penten-2-one 
• 456-03-1 1-(4-fluorophenyl)propan-1-one 
• 75175-77-8 3-(dimethylamino)-1-(4-fluorophenyl)prop-2-en-1-one 

Downstream Products

• 1001845-02-8 C₁₄H₁₁BrFNO 

Relevant academic research and scientific papers

Synthetic method of 3-acyl pyridine compound

The invention discloses a 3-acyl pyridine compound synthetic method, which belongs to the technical field of organic synthesis. The synthetic method takes an enaminone compound and an alpha, beta-saturated ketone compound or an alpha, beta-saturated aldeh

Synthesis of Functionalized Pyridines via Cu(II)-Catalyzed One-Pot Cascade Reactions of Inactivated Saturated Ketones with Electron-Deficient Enamines

In this paper, a novel and efficient synthesis of 3-acylpyridines and pyridine-3-carboxylates through the oxidative one-pot sequential reactions of inactivated saturated ketones with electron-deficient enamines is presented. Mechanistically, the formation of the title compounds involves the in situ formation of an enone intermediate through an oxidative dehydrogenation of the saturated ketone substrate, followed by its [3+3] annulation with β-enaminone or β-enaminoester via a cascade process, including Michael addition, aldol type condensation, and oxidative aromatization.

Cu-Catalyzed Three-Component Cascade Annulation Reaction: An Entry to Functionalized Pyridines

A concise copper-catalyzed N-O bond cleavage/C-C/C-N bond formation procedure has been described for the synthesis of multisubstituted pyridines. Various oxime acetates, activated methylene compounds, and a wide range of aldehydes bearing aryl, heteroaryl, vinyl, and trifluoromethyl groups were employed to provide the tri- or tetrasubstituted pyridines with flexible substitution patterns. Moreover, this method features inexpensive catalysts, no need for extra oxidant, and high step-enconomy, which make it pratical and attractive.

Microwave assisted synthesis of 6-aryl-2-methyl-3-[benzothiazinylpyridinyl / 2-aminopyrimidinyl / 2-aminothiazolyl / triazolothiadiazinyl]pyridines

A number of new 6-Aryl-2-methyl-3-[benzothiazinylpyridinyl / 2-amino pyrimidinyl / 2-aminothiazolyl and triazolothiadiazinyl] pyridines (4 - 7) have been synthesized under microwave irradiation conditions.