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75175-78-9

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75175-78-9 Usage

General Description

The chemical compound "1-(2-Chlorophenyl)-3-(dimethylamino)-2-propen-1-one" is also known as Clonidine, and it is a prescription medication used to manage conditions such as high blood pressure and attention deficit hyperactivity disorder (ADHD). It works by stimulating alpha receptors in the brain and central nervous system, which leads to a decrease in blood pressure and a reduction in hyperactivity and impulsivity. Clonidine is classified as a centrally acting alpha-agonist hypotensive agent and is available in various forms, including tablets, patches, and injections. It is important to note that Clonidine should only be used under the supervision of a healthcare professional due to its potential for side effects and drug interactions.

Check Digit Verification of cas no

The CAS Registry Mumber 75175-78-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,7 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 75175-78:
(7*7)+(6*5)+(5*1)+(4*7)+(3*5)+(2*7)+(1*8)=149
149 % 10 = 9
So 75175-78-9 is a valid CAS Registry Number.

75175-78-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75175-78-9 SDS

75175-78-9Relevant articles and documents

An expedient synthesis of highly functionalized 1,3-dienes by employing cyclopropenes asC4units

Jiang, Chengzhou,Wu, Jiamin,Han, Jiabin,Chen, Kai,Qian, Yang,Zhang, Zhengyu,Jiang, Yaojia

supporting information, p. 5710 - 5713 (2021/06/16)

An efficient method has been described to synthesize dicarbonyl functionalized 1,3-dienes by cleaving the CC bond of enaminones with cyclopropenes in the presence of a rhodium catalyst. The acetate-substituted cyclopropenes are judiciously chosen as standardC4units of 1,3-diene precursors. The reactions are believed to undergo a unique cutting and insertion process, involving a CC bond cleavage of the enaminone and insertion of a newC(sp2) source with the formation of two C-C single bonds. A broad range of substrates can be used to synthesize the corresponding 1,3-dienes under very mild reaction conditions, including low catalyst-loading, ambient temperature, and a neutral reaction solvent.

Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation

Debenham, John S.,Madsen-Duggan, Christina B.,Wang, Junying,Tong, Xinchun,Lao, Julie,Fong, Tung M.,Schaeffer, Marie-Therese,Xiao, Jing Chen,Huang, Cathy C.R.-R.,Shen, Chun-Pyn,Sloan Stribling,Shearman, Lauren P.,Strack, Alison M.,Euan MacIntyre,Hale, Jeffrey J.,Walsh, Thomas F.

scheme or table, p. 2591 - 2594 (2009/12/25)

The synthesis, SAR and binding affinities are described for cannabinoid-1 receptor (CB1R) specific inverse agonists based on pyridopyrimidine and heterotricyclic scaffolds. Food intake and pharmacokinetic evaluation of several of these compounds indicate

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