75176-38-4Relevant academic research and scientific papers
Synthesis of (+/-)-2,3-Methanoproline: A Novel Inhibitor of Ethylene Biosynthesis
Switzer, Frank L.,Halbeek, Herman Van,Holt, Elizabeth M.,Stammer, Charles H.,Saltveit, Mikal E.
, p. 6091 - 6100 (1989)
The title compound, 2-aza-bicyclohexane-1-carboxylic acid (2) was prepared by treatment of N-benzyloxycarbonyl-2,3-dehydroproline tert-butyl ester with diazomethane followed by photolysis of the resulting pyrazoline and deprotection.Its N-acetyl-N'-methyl amide, a peptide mimic, was synthesized and the structure of was confirmed by X-ray diffraction studies.NMR spectroscopy was also used to examine the effect of the cyclopropane ring on its conformation.This 2,3-methanoamino acid (2) was found to be a weak inhibitor of ethylene biosynthesis in cucumber cotyledon strips and germinating squash seeds.The data show that 2 probably inhibits the conversion of 1-aminocyclopropanecarboxylic acid to ethylene in these tissues.
MERCAPTOACYL DERIVATIVES OF SUBSTITUTED PROLINES
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, (2008/06/13)
New mercaptoacyl derivatives of substituted prolines which have the general formula STR1 are useful as hypotensive agents.
MERCAPTOACYL DERIVATIVES OF 3-SUBSTITUTED PROLINE DERIVATIVES
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, (2008/06/13)
New mercaptoacyl derivatives of 3-substituted proline derivatives are provided which have the general formula STR1 and are useful as hypotensive agents.
