75191-50-3 Usage
Chemical class
Pyrimidine nucleosides
Explanation
The compound belongs to a class of nucleosides that contain a pyrimidine base.
Explanation
The compound is composed of a pyrimidine base (a type of nitrogen-containing ring structure) connected to a deoxyribose sugar (a sugar molecule lacking one oxygen atom).
Explanation
A methylamino group (a nitrogen atom bonded to a methyl group) is attached to the sugar ring, which is a modification of the standard deoxyribose sugar.
Explanation
The compound has potential applications in the development of pharmaceuticals due to its antiviral and antitumor properties.
Explanation
The compound is known to exhibit antiviral properties, which means it can help inhibit the replication of viruses within host cells.
Explanation
The compound also has antitumor properties, which means it can potentially help suppress the growth of tumors in the body.
Explanation
The compound serves as a precursor in the synthesis of various nucleoside analogs, which are modified versions of naturally occurring nucleosides.
Explanation
Research is currently being conducted to further explore the biological activities and potential therapeutic uses of 1-[2,5-dideoxy-5-(methylamino)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione in the field of medicine.
Structure
Pyrimidine base linked to a deoxyribose sugar
Modification
Methylamino group attached to the sugar ring
Applications
Pharmaceutical industry
Antiviral properties
Inhibits viral replication
Antitumor properties
Suppresses tumor growth
Precursor
Used in the synthesis of nucleoside analogs
Ongoing research
Biological activities and therapeutic uses
Check Digit Verification of cas no
The CAS Registry Mumber 75191-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,9 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75191-50:
(7*7)+(6*5)+(5*1)+(4*9)+(3*1)+(2*5)+(1*0)=133
133 % 10 = 3
So 75191-50-3 is a valid CAS Registry Number.
75191-50-3Relevant academic research and scientific papers
Oligonucleotide analogues bearing an acyclonucleoside linked by an internucleotide amide bond
Kochetkova,Fillipova,Kolganova,Timofeev,Florentiev
, p. 207 - 214 (2008/09/19)
Oligonucleotide analogues bearing an acyclocytidine linked to thymidine with an amide (3′-O-CH2CO-N-5′) bond were synthesized. Melting curves of duplexes formed by modified oligonucleotides and complementary natural oligomers were obtained and
Synthesis and hybridization properties of amide-linked thymidine dimers incorporated into oligodeoxynucleotides
Idziak, Irene,Just, George,Damha, Masad J.,Giannaris, Paul A.
, p. 5417 - 5420 (2007/10/02)
Thymidine dimers, connected by amide or N-methyl amide linkages, have been prepared. The dimers have each been incorporated three times into normal strands of DNA by solid phase synthesis. Thermal denaturation studies indicated that these modifications ca
