75197-99-8

Upstream product

• 69-96-5 threo-2-amino-3-hydroxy-3-phenylpropanoic acid 
• 64300-27-2 cis-(+/-)-3-phenylaziridine-2-carbonitrile 
• 67-63-0 isopropyl alcohol 
• 79559-53-8 threo-2-amino-3-fluoro-3-phenylpropionic acid amide 
• 88286-26-4 α,β-dibromocinnamonitrile 
• 79559-52-7 cis-2-phenylaziridine-3-carboxylic acid amide 
• 19922-81-7 2,3-dibromo-3-phenyl-propionic acid amide 
• 621-79-4 cinnamamide 
• 73475-94-2 3-phenyl-aziridine-2-carboxylic acid isopropyl ester 

Downstream Products

• 93863-35-5 threo-2-(dichloroacetamido)-3-fluoro-3-(m-nitrophenyl)-1-propanol 
• 93863-34-4 threo-2-(dichloroacetamido)-3-fluoro-3-(o-nitrophenyl)-1-propanol 
• 93863-36-6 threo-2-(dichloroacetamido)-3-fluoro-3-(p-nitrophenyl)-1-propanol 
• 93863-40-2 2,2-Dichloro-N-(2-fluoro-1-hydroxymethyl-2-phenyl-ethyl)-acetamide 
• 93863-37-7 N-[1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-fluoro-2-(3-nitro-phenyl)-ethyl]-2,2-dichloro-acetamide 
• 93863-38-8 N-[1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-fluoro-2-(4-nitro-phenyl)-ethyl]-2,2-dichloro-acetamide 
• 76532-81-5 2-Acetylamino-3-fluoro-3-phenyl-propionic acid isopropyl ester 

Relevant academic research and scientific papers

Reaction of Hydrogen Fluoride in Pyridine Solution with cis-Cyano-2- and cis-Amido-2-aziridines. Preparation of β-Fluoro-α-amino Acids and Esters by Means of Acidic Hydrolysis and Alcoholysis of β-Fluoro-α-Amino Nitriles and/or β-Fluoro-α-Amino Acid Amide

The addition of hydrogen fluoride generated from pyridinium poly(hydrogen fluoride) (i.e.Olah's reagent) to some cis-2-cyano- and cis-2-amido-aziridines has been examined.The reaction led to fluoroamine derivatives which upon acidic hydrolysis and alcohol

Preparation of Fluoro Amines by the Reaction of Aziridines with Hydrogen Fluoride in Pyridine Solution

Hydrogen fluoride combines regiospecifically with aziridines (1) to give 2-fluoro amines (6) in good yields.Fluorine attack is in all cases completely directed to the most substituted ring carbon or to the benzylic carbon.The results, for benzylic aziridi

DETERMINATION OF THREO AND ERYTHRO CONFIGURATIONS OF 3-FLUOROPHENYLALANINE FOR VERIFYING STEREOCHEMICAL ASPECTS OF RECENTLY REPORTED SYNTHESES

Determination of threo and erythro configurations of both diastereoisomers of 3-fluorophenylalanine on the basis of chemical transformation and X-ray analysis has confirmed that the aziridine ring opening reaction gives the threo isomer stereoselectively, whereas the fluorodehydroxylation reaction affords both isomers nonselectively.