75201-06-8

Upstream product

• 75201-02-4 2-[5-(4-Chloro-phenyl)-4,5-dihydro-1H-pyrazol-3-yl]-4-methyl-phenol 
• 16635-10-2 1-(p-chlorophenyl)-3-(2-hydroxy-5-methylphenyl)prop-1-en-3-one 
• 75227-44-0 2'-Hydroxy-5'-methyl-4-chlorochalkone α,β-dibromide 

Relevant academic research and scientific papers

Synthesis of pyrazole and isoxazole in triethanolamine medium

Reactions of 2′-hydroxy chalcone dibromides 2a-1 with phenyl hydrazine and hydrazine hydrate afford pyrazoles 1a-1 and with hydroxylamine hydrochloride give isoxazoles 5a-f in triethanolamine medium. Similarly reaction of β-diketone 3b-e with phenyl hydra

Synthesis and Antimicrobial Activity of Hydroxyarylpyrazoles

Hydroxyarylpyrazolines (III) and Pyrazoles (IV) have been synthesized.Compounds IVa and IVd exhibit marked antifungal activity against A. niger, C. albicans, C. neoformans, T. mentagraphytes and M. canis whereas compound IVc shows activity against the last three fungi.None of the compounds shows any noteworthy antibacterial activity against Staphy. aureus, Staphi. typhi and Esch. coli even at 100 μg/ml.