16635-10-2

Basic information

• Product Name: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)-
• CAS NO: 16635-10-2
• Molecular Formula: C16H13ClO2
• Molecular Weight: 272.731
• Mol File: 16635-10-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)-(16635-10-2)
• EPA Substance Registry System: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(2-hydroxy-5-methylphenyl)-(16635-10-2)

Safety Data

• Hazardous Substances Data: 16635-10-2(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 86882-00-0 2-[2-(4-Chloro-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl]-4-methyl-phenol 
• 89112-22-1 C₁₇H₁₃ClN₂OS 
• 1233481-35-0 C₁₇H₁₃ClN₂O₂ 
• 60402-30-4 2-(4-chlorophenyl)-6-methyl-4H-chromen-4-one 
• 14166-16-6 2-(4-chlorophenyl)-6-methylchroman-4-one 
• 1266399-49-8 C₁₇H₁₆ClN₃O₂ 
• 1266399-37-4 4-(4-chlorophenyl)-8-methyl-4H-chromeno[4,3-d][1,2,3]selenadiazole 
• 60402-31-5 6-Bromomethyl-2-p-chlorophenylchromone 

Relevant articles and documents

Iodine-mediated direct synthesis of 3-iodoflavones

Molecular iodine has been used for the regioselective, one pot, direct synthesis of 3-iodoflavones from 2′-allyloxy chalcones, 2′-hydroxy chalcones and flavones. Allyl deprotection, cyclization dehydrogenation and α-iodination of 2′-allyloxychalcones has been achieved in a single step to offer 3-iodoflavones.

Absorption and fluorescent studies of 3-hydroxychromones

The synthesis and spectral studies of variously substituted 3-hydroxychromones have been carried out. A key relationship between the structural motif of synthesized 3-hydroxychromones (3-HCs) and their fluorescent properties was found. The chromones substituted with electron-donating group at 4′-position expressed the red shift of the N and T band and also exhibited the increased fluorescent intensity ratio while the chromones with electron-withdrawing group showed the blue shift of the N and T band. Therefore, these 3-HCs may behave as the possible fluorescent probes.

Synthesis of some new pyrimidines and isoxazolines and their pharmacological activity

The condensation of 5-methyl-2-hydroxy acetophenone 1 with different aromatic aldehydes in anhyd ethanol in presence of strong alkali gave 1-(5′-methyl-2′-hydroxy phenyl-1′-yl)-3-substituted arylidene-2-propen-1-ones (2a-d). Compounds (2a-d) underwent cyc