75209-54-0

Basic information

• Product Name: 1-(3-methoxyphenyl)cycloheptene
• CAS NO: 75209-54-0
• Molecular Formula: C₁₄H₁₈O
• Molecular Weight: 202.2921
• Mol File: 75209-54-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 314.3°C at 760 mmHg
• Flash Point: 123.1°C
• Density: 0.993g/cm³
• Vapor Pressure: 0.000868mmHg at 25°C
• Refractive Index: 1.53
• CAS DataBase Reference: 1-(3-methoxyphenyl)cycloheptene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-methoxyphenyl)cycloheptene(75209-54-0)
• EPA Substance Registry System: 1-(3-methoxyphenyl)cycloheptene(75209-54-0)

Safety Data

• Hazardous Substances Data: 75209-54-0(Hazardous Substances Data)

Usage

General Description

1-(3-methoxyphenyl)cycloheptene is a chemical compound with the molecular formula C14H18O. It is a cyclic hydrocarbon that contains a cycloheptene ring with a methoxyphenyl group attached to the first carbon atom. 1-(3-methoxyphenyl)cycloheptene is often used as a building block in organic synthesis and can be converted into various other compounds through different chemical reactions. It is also used in pharmaceutical research and development for the synthesis of potential drug candidates. 1-(3-methoxyphenyl)cycloheptene is a colorless liquid with a faint odor and is flammable at high temperatures. It is important to handle this chemical with caution as it may be harmful if swallowed, inhaled, or in contact with skin.

Upstream product

• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 502-42-1 cycloheptanone 
• 2398-37-0 3-methoxyphenyl bromide 
• 2082-28-2 1-(m-methoxyphenyl)cycloheptanol 

Downstream Products

• 107620-60-0 cyclohex-1-en-1-yl(3-methoxyphenyl)methanone 
• 2914-77-4 (±)-(1R,2S)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol 
• 27203-92-5 cis-tramadol 
• 75210-20-7 3-((1R,6S,10S)-10-Methylamino-bicyclo[4.3.1]dec-1-yl)-phenol; hydrobromide 
• 75209-78-8 (1S,6R,7R,10R)-6-(3-Methoxy-phenyl)-10-methylamino-bicyclo[4.3.1]decan-7-ol 
• 75209-78-8 9-endo-hydroxy-1-(m-methoxyphenyl)-10-endo-methylaminobicyclo<4.3.1>decane 
• 75209-63-1 10-endo-amino-9-endo-hydroxy-1-(m-methoxyphenyl)bicyclo<4.3.1>decane 
• 75210-00-3 10-endo-amino-9-endo-hydroxy-1-(m-hydroxyphenyl)bicyclo<4.3.1>decane 
• 75209-85-7 [(1R,6S,10R)-1-(3-Methoxy-phenyl)-bicyclo[4.3.1]dec-10-yl]-methyl-amine 
• 75209-85-7 [(1R,6S,10S)-1-(3-Methoxy-phenyl)-bicyclo[4.3.1]dec-10-yl]-methyl-amine 
• 75209-71-1 10-endo-amino-1-(m-methoxyphenyl)bicyclo<4.3.1>decane 
• 75209-65-3 5-aminomethyl-1-(m-methoxyphenyl)-1-cyclononene 
• 75209-58-4 4-[1-(3-Methoxy-phenyl)-9-oxo-bicyclo[4.3.1]dec-10-ylidene]-morpholin-4-ium; chloride 
• 75210-06-9 [(1R,6S,10S)-1-(3-Methoxy-phenyl)-bicyclo[4.3.1]dec-10-yl]-methyl-phenethyl-amine; hydrobromide 

Relevant articles and documents

Pd-catalyzed cross-coupling of highly sterically congested enol carbamates with grignard reagents via c-o bond activation

The palladium-catalyzed cross-coupling reaction of enol carbamates to construct highly sterically congested alkenyl compounds is presented for the first time. This protocol demonstrates the potential of using thermally stable and highly atom-economic enol electrophiles as building blocks in bulky alkene synthesis. This reaction accommodates a broad substrate scope with excellent Z/E isomer ratios, which also provides a new synthetic pathway for accessing Tamoxifen.

Well-defined air-stable palladium HASPO complexes for efficient Kumada-Corriu cross-couplings of (Hetero)aryl or alkenyl tosylates

Palladium complexes of representative heteroatom-substituted secondary phosphine oxide (HASPO) preligands were synthesized and fully characterized, including X-ray crystal structure analysis. Importantly, these well-defined complexes served as highly efficient catalysts for Kumada-Corriu cross-coupling reactions of aryl, alkenyl, and even heteroaryl tosylates. Particularly, an air-stable catalyst derived from inexpensive PinP(O)H displayed a remarkably high catalytic efficacy, which resulted in cross-couplings at low catalyst loadings under exceedingly mild reaction conditions with ample scope.