75209-54-0

Usage

Uses

Used in Organic Synthesis:
1-(3-methoxyphenyl)cycloheptene is used as a building block in organic synthesis for the creation of various compounds. Its unique structure allows for a wide range of chemical reactions, making it a valuable component in the development of new molecules with diverse applications.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, 1-(3-methoxyphenyl)cycloheptene is used as a key component in the synthesis of potential drug candidates. Its versatility in chemical reactions enables the exploration of new therapeutic agents with the potential to address various medical conditions.
Used in Chemical Research:
1-(3-methoxyphenyl)cycloheptene is also utilized in chemical research to study the properties and reactivity of cycloheptene rings and methoxyphenyl groups. This knowledge can contribute to the advancement of synthetic chemistry and the development of novel compounds with specific applications in various industries.

Upstream product

• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 502-42-1 cycloheptanone 
• 2398-37-0 3-methoxyphenyl bromide 
• 2082-28-2 1-(m-methoxyphenyl)cycloheptanol 

Downstream Products

• 107620-60-0 cyclohex-1-en-1-yl(3-methoxyphenyl)methanone 
• 2914-77-4 (±)-(1R,2S)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol 
• 27203-92-5 cis-tramadol 
• 75210-20-7 3-((1R,6S,10S)-10-Methylamino-bicyclo[4.3.1]dec-1-yl)-phenol; hydrobromide 
• 75209-78-8 (1S,6R,7R,10R)-6-(3-Methoxy-phenyl)-10-methylamino-bicyclo[4.3.1]decan-7-ol 
• 75209-78-8 9-endo-hydroxy-1-(m-methoxyphenyl)-10-endo-methylaminobicyclo<4.3.1>decane 
• 75209-63-1 10-endo-amino-9-endo-hydroxy-1-(m-methoxyphenyl)bicyclo<4.3.1>decane 
• 75210-00-3 10-endo-amino-9-endo-hydroxy-1-(m-hydroxyphenyl)bicyclo<4.3.1>decane 
• 75209-85-7 [(1R,6S,10R)-1-(3-Methoxy-phenyl)-bicyclo[4.3.1]dec-10-yl]-methyl-amine 
• 75209-85-7 [(1R,6S,10S)-1-(3-Methoxy-phenyl)-bicyclo[4.3.1]dec-10-yl]-methyl-amine 
• 75209-71-1 10-endo-amino-1-(m-methoxyphenyl)bicyclo<4.3.1>decane 
• 75209-65-3 5-aminomethyl-1-(m-methoxyphenyl)-1-cyclononene 
• 75209-58-4 4-[1-(3-Methoxy-phenyl)-9-oxo-bicyclo[4.3.1]dec-10-ylidene]-morpholin-4-ium; chloride 
• 75210-06-9 [(1R,6S,10S)-1-(3-Methoxy-phenyl)-bicyclo[4.3.1]dec-10-yl]-methyl-phenethyl-amine; hydrobromide 

Relevant academic research and scientific papers

Pd-catalyzed cross-coupling of highly sterically congested enol carbamates with grignard reagents via c-o bond activation

The palladium-catalyzed cross-coupling reaction of enol carbamates to construct highly sterically congested alkenyl compounds is presented for the first time. This protocol demonstrates the potential of using thermally stable and highly atom-economic enol electrophiles as building blocks in bulky alkene synthesis. This reaction accommodates a broad substrate scope with excellent Z/E isomer ratios, which also provides a new synthetic pathway for accessing Tamoxifen.

Biomimetic synthesis of Tramadol

Tramadol has recently been isolated from the roots and bark of Nauclea latifolia. A plausible biosynthetic pathway has been proposed and the product-precursor relationship has been probed by 13C position-specific isotope analysis. By further exploring this pathway, we demonstrate that a key step of the proposed pathway can be achieved using mild conditions that mimic in vivo catalysis.

Well-defined air-stable palladium HASPO complexes for efficient Kumada-Corriu cross-couplings of (Hetero)aryl or alkenyl tosylates

Palladium complexes of representative heteroatom-substituted secondary phosphine oxide (HASPO) preligands were synthesized and fully characterized, including X-ray crystal structure analysis. Importantly, these well-defined complexes served as highly efficient catalysts for Kumada-Corriu cross-coupling reactions of aryl, alkenyl, and even heteroaryl tosylates. Particularly, an air-stable catalyst derived from inexpensive PinP(O)H displayed a remarkably high catalytic efficacy, which resulted in cross-couplings at low catalyst loadings under exceedingly mild reaction conditions with ample scope.