7521-38-2

Usage

Uses

Used in Food Industry:
2,6-Dimethyl-3-acetyl-4H-pyran-4-one is used as a flavoring agent for its ability to enhance the taste of various food products, such as desserts, candies, and beverages. Its caramel-like aroma and flavor make it a popular choice for adding depth and richness to these items.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-Dimethyl-3-acetyl-4H-pyran-4-one is used as a flavoring additive in oral medications, improving the taste and palatability of these products for patients.
Used in Cosmetic and Personal Care Products:
2,6-Dimethyl-3-acetyl-4H-pyran-4-one is also used as a fragrance ingredient in cosmetic and personal care products, contributing to their overall scent profile and consumer appeal.
Safety and Regulatory Approval:
2,6-Dimethyl-3-acetyl-4H-pyran-4-one is considered safe for consumption and has been approved for use in food and fragrance applications by regulatory agencies, ensuring its widespread acceptance and use in various industries.

Upstream product

• 108-24-7 acetic anhydride 
• 1493-13-6 trifluorormethanesulfonic acid 
• 75-05-8 acetonitrile 
• 108-22-5 Isopropenyl acetate 

Downstream Products

• 97066-64-3 2-Acetyl-5-hydroxy-5-methyl-3-morpholino-2-cyclohexenon 
• 125247-11-2 2-Acetyl-5-hydroxy-5-methyl-3-(N'-benzylpiperazino)-2-cyclohexenon 
• 97066-60-9 2-Acetyl-3-dimethylamino-5-hydroxy-5-methyl-2-cyclohexenon 
• 97066-14-3 2-Hydroxy-4-methyl-6-<4-(3-trifluormethylphenyl)-piperazino>-acetophenon 
• 97066-01-8 N-(2-Acetyl-5-hydroxy-5-methyl-3-oxo-2-cyclohexenyl)-glycinethylester 
• 97066-00-7 2-Acetyl-3-benzylamino-5-hydroxy-5-methyl-2-cyclohexenon 
• 97066-21-2 7-Hydroxy-4,7-dimethyl-2-phenyl-5,6,7,8-tetrahydrochinazolin-5-on 
• 97066-22-3 6-Hydroxy-3,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-2H-indazol-4-on 
• 97066-03-0 2-Acetyl-3-(2,2-dimethylhydrazino)-5-hydroxy-5-methyl-2-cyclohexenon 
• 97065-99-1 2-Acetyl-3-amino-5-hydroxy-5-methyl-2-cyclohexenon 
• 125247-13-4 2-Acetyl-5-hydroxy-5-methyl-3-(1,2,3,4-tetrahydroisochinolino)-2-cyclohexenon 
• 97066-63-2 2-Acetyl-5-hydroxy-5-methyl-3-piperidino-cyclohexenon 

Relevant academic research and scientific papers

Interaction of acetonitrile with trifluoromethanesulfonic acid: Unexpected formation of a wide variety of structures

Interaction of acetonitrile with trifluoromethanesulfonic acid has been studied by multinuclear NMR and ESI-MS. It has been found that the interaction results in formation of a great variety of different cations and neutral compounds which is controlled by the ratio of CH3CN to TfOH. In the presence of an excess of the acid (molar ratio 1:8-14) diprotonated N-acetylacetamidine 1 is formed as the major product, which eventually transforms into protonated acetamidine 3 and acetic acid 4. At molar ratio of (1:1-2) diprotonated 2,4-dimethyl-6-methylidene-3H-1,3,5-triazine 12, tautomer of the diprotonated trimethyl-s-triazine 11, becomes the main product at an early stage of the reaction and diprotonated 1-(dimethyl-1,3,5-triazin-2-yl) prop-1-en-2-ol 15 at a later stage. In the case of a large excess of acetonitrile (4-20:1) trication 17 is formed as a result of the interaction between 11 and 12 along with some oligomers [(CH3CN) 3]n (n = 4-12). The Royal Society of Chemistry 2012.

Unusual aluminum chloride-assisted conversion of isopropenyl acetate into 3-acetyl- and 3,5-diacetyl-2,6-dimethyl-4H-pyran-4-ones

Reflux of isopropenyl acetate with an excess of AlCl3 in 1,2-dichloroethane affords 3,5-diacetyl-2,6-dimethyl-4H-pyran-4-one in 17% yield. The mild acidic cleavage of the latter (2% HCl, 20°C, 16 h) gives 3-acetyl-2,6-dimethyl-4H-pyran-4-one in 87% yield, whereas this reaction under more drastic conditions (17% HCl, reflux, 3 h) gives 2,6-dimethyl-4H-pyran-4-one in 61% yield.