75218-45-0

Basic information

• Product Name: N-(3-thienyl-β-ethyl)-4-benzyloxy-3-methoxyphenylacetamide
• Synonyms: N-(3-thienyl-β-ethyl)-4-benzyloxy-3-methoxyphenylacetamide
• CAS NO: 75218-45-0
• Molecular Weight: 381.496
• Mol File: 75218-45-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-thienyl-β-ethyl)-4-benzyloxy-3-methoxyphenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-thienyl-β-ethyl)-4-benzyloxy-3-methoxyphenylacetamide(75218-45-0)
• EPA Substance Registry System: N-(3-thienyl-β-ethyl)-4-benzyloxy-3-methoxyphenylacetamide(75218-45-0)

Safety Data

• Hazardous Substances Data: 75218-45-0(Hazardous Substances Data)

Upstream product

• 59311-67-0 2-(3-thienyl)ethylamine 
• 29973-91-9 4-benzyloxy-3-methoxyphenylacetic acid 

Downstream Products

• 781565-01-3 7-(4'-benzyloxy-3'-methoxybenzyl)-4,5,6,7-tetrathieno<2,3-c>pyridine 
• 688301-90-8 9-benzyloxy-10-methoxy-7H-4,5,12,12a-tetahydrobenzothieno<2,3-a>quinolizine 
• 75218-51-8 8-Benzyloxy-9-methoxy-4,6,11,11a-tetrahydro-5H-1-thia-5a-aza-cyclopenta[a]anthracene; hydrochloride 
• 75218-49-4 7-(4-Benzyloxy-3-methoxy-benzyl)-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine; hydrochloride 
• 75218-47-2 7-(4'-benzyloxy-3'-methoxybenzyl)-4,5-dihydrothieno<2,3-c>pyridine hydrochloride 

Relevant articles and documents

STUDIES ON HETEROCYCLIC COMPOUNDS VI. Synthesis of Thiophene Isoesters of Protoberberine Alkaloids

Synthesis of thiophene isosters of protoberberine alkaloids (6, 12, 19) is described.The Mannich type reaction of the tetrahydroisoquinolines (5, 11) and the thienopyridine (18) with formaldehyde in glacial acetic acid afforded the title compounds.Cyclization of the tetrahydroisoquinoline derivative (23) failed to furnish the D-ring protoberberine isoster (25), but gave an unexpected product, the oxazepinoisoquinoline derivative (24).The conversion of the compound (24) to the 2-substituted isoquinoline (27) is also described.