752225-79-9Relevant academic research and scientific papers
Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells
Walter, Georg,Liebl, Renate,Von Angerer, Erwin
, p. 634 - 644 (2007/10/03)
Estrone sulfate (E1S) is an endogenous prodrug that delivers estrone and, subsequently, estradiol to target cells, after hydrolysis by the enzyme estrone sulfatase, which is active in various tissues including hormone-dependent breast cancer. Blockade of
