75225-88-6

Upstream product

• 75225-85-3 cybrodal 
• 75225-92-2 methyl cybrodate 
• 79801-78-8 O-acetylcybrodal 
• 79801-66-4 isocybrodol methyl ether 
• 79801-65-3 cybrodol methyl ether 
• 74973-59-4 methyl 3-(2-(tetrahydro-2H-pyran-2-yl)oxyethyl)-6-methyoxymethyl-2,4-dimethylbenzoate 
• 74973-57-2 1-bromo-3(2-(tetrahydro-2H-pyran-2-yl)oxyethyl)-6-methoxymethyl-2,4-dimethylbenzene 
• 75225-86-4 cybrodic acid 
• 79801-57-3 2-(3-bromo-4-methoxymethyl-2,6-dimethylphenyl)ethanol 
• 74973-56-1 2-(4-methoxymethyl-2,6-dimethylphenyl)ethanol 
• 75225-90-0 Acetic acid 4-(2-acetoxy-ethyl)-2-((Z)-3-acetoxy-2-methyl-propenyl)-3,5-dimethyl-benzyl ester 
• 79801-70-0 3-((3-(2-acetoxyethyl)-6-bromomethyl-2,4-dimethyl)phenyl)-2-methyl-(Z)-2-propenyl bromide 
• 79801-60-8 3-(2-(tetrahydro-2H-pyran-2-yl)oxyethyl)-6-methoxymethyl-2,4-dimethylbenzaldehyde 

Downstream Products

• 79801-78-8 O-acetylcybrodal 
• 75225-90-0 O,O,O-triacetylcybrodol 
• 75225-85-3 cybrodal 

Relevant academic research and scientific papers

Electrophilic cyclization of 1,5-enynes

Figure Presented Valuable six-membered carbocycles including highly substituted benzenes, 1,4-cyclohexadienes, and 4-fluorocyclohexenes can be prepared from simple 1,5-enynes by iodonium-induced cyclization. This cyclization strategy was applied to the total synthesis of cybrodol, a sesquiterpenoid with a pentasubstituted aromatic core (see scheme).