75230-39-6

Upstream product

• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 
• 6482-24-2 2-Bromoethyl methyl ether 
• 67-56-1 methanol 
• 62176-27-6 5-chloro-2-(2-methoxyethoxy)benzoic acid 

Downstream Products

• 75230-22-7 N-[5-Chloro-2-(2-methoxy-ethoxy)-benzoyl]-N'-cyclooctyl-guanidine; hydrochloride 
• 62176-27-6 5-chloro-2-(2-methoxyethoxy)benzoic acid 
• 1271524-43-6 5-chloro-N-(5-(2,6-dichlorophenyl)-2-oxo-2,3-dihydro-1H-benzo[e] [1,4]diazepin-3-yl)-2-(2-methoxyethoxy)benzamide 

Relevant academic research and scientific papers

AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS

The present invention concerns a compound of formula (I): or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the kinase ERK activity in particular ERK2 activity.

BENZODIAZEPINE DERIVATIVES FOR TREATING HEPATITIS C INFECTION

The invention concerns benzodiazepine derivatives of Formula (I) wherein W, X, L1, L2, L3, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment or prophylaxis of hepatitis C virus infection.

1-ACYL-3-CYCLOOCTYLGUANIDINES

On reaction of cyclooctylamine with the sulfate of S-methylisothiourea cyclooctylguanidine was formed which was acylated with the methyl esters of 5-halogeno- and 3,5-dihalogeno-2-alkoxybenzoic acids.The 1-acyl-3-cyclooctylguanidine I-XVII formed were tes