75245-67-9

Basic information

• Product Name: Benzeneethanol, a-(1-methylethyl)-a-(phenylmethyl)-
• CAS NO: 75245-67-9
• Molecular Formula: C18H22O
• Molecular Weight: 254.372
• Mol File: 75245-67-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, a-(1-methylethyl)-a-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, a-(1-methylethyl)-a-(phenylmethyl)-(75245-67-9)
• EPA Substance Registry System: Benzeneethanol, a-(1-methylethyl)-a-(phenylmethyl)-(75245-67-9)

Safety Data

• Hazardous Substances Data: 75245-67-9(Hazardous Substances Data)

Upstream product

• 102-04-5 1,3-Diphenylpropanone 
• 1068-55-9 isopropylmagnesium chloride 
• 100-39-0 benzyl bromide 
• 97-62-1 Ethyl isobutyrate 
• 920-39-8 isopropylmagnesium bromide 
• 547-63-7 Methyl isobutyrate 
• 100-44-7 benzyl chloride 
• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 74202-34-9 (E)-2-Benzyl-3-methyl-1-phenyl-1-buten 
• 857824-87-4 2-benzyl-2-isopropyl-3-phenyl-oxirane 
• 64278-89-3 4-methyl-1,2-diphenylpentan-3-one 
• 74202-33-8 (Z)-2-Benzyl-3-methyl-1-phenyl-1-buten 

Relevant articles and documents

Development of a Scalable Lanthanide Halide/Quaternary Ammonium Salt System for the Nucleophilic Addition of Grignard Reagents to Carbonyl Groups and Application to the Synthesis of a Remdesivir Intermediate

This manuscript describes the development and implementation of a scalable additive system, consisting of a lanthanide salt and a solubilizing quaternary ammonium salt, to improve the yield and robustness of the addition of an organomagnesium reagent to a

Solutions of anhydrous lanthanide salts and its preparation

The present invention relates to anhydrous solutions of MX 3 €￠z LiA in a solvent, wherein M is a lanthanide including lanthanum, or yttrium or indium; z > 0; and X and A are independently or both monovalent anions, preferably Cl, Br or I. The solution is readily prepared by dissolving or suspending MX 3 or its hydrate and z equiv LiA in water or hydrophilic solvents, or mixtures thereof, removing the solvent under vacuum and dissolving the resulting powder in another solvent. The solution of MX 3 €￠z LiA can advantageously be used e.g. in addition reactions of Grignard reagents to ketones and imines. Even the catalytic use of MX 3 €￠z LiA is possible. Also claimed are a method for preparing the anhydrous solutions, the use of such solution in a chemical reaction and chemical compositions MX 3 €￠z LiA, with M, z, X and A as indicated above.

Some uses of mischmetall in organic synthesis

Mischmetall, an alloy of the light lanthanides, has been used in a variety of organic reactions, either as a coreductant in samarium(II)-mediated reactions (Barbier and Grignard-type reactions, pinacolic coupling reactions) or as the promoter of Reformatsky-type reactions. It has been also employed as the starting material for easy syntheses of lanthanide trihalides, the reactivity of which has been explored in Imamoto and Luche-Fukuzawa reactions and in Mukaiyama aldol reactions.