75259-72-2

Upstream product

• 75259-82-4 1-Phenyl-3-(2-pyridin-4-yl-ethyl)-1H-indole 
• 100-43-6 4-vinylpyridine 
• 16096-33-6 1-phenyl-1H-indole 

Relevant academic research and scientific papers

3-(4-Piperidinylalkyl)indoles, Selective Inhibitors of Neuronal 5-Hydroxytryptamine Uptake

A series 3-(4-piperidinylalkyl)indoles was synthesized and tested as uptake inhibitors of biogenic amines.Some of these compounds are potent and very selective in blocking the 5-hydroxytryptamine (5-HT) uptake, as evidenced by biochemical data and behavioral tests.A discussion on structure-activity relationships is given.The most interesting member of the series, indalpine, 3-indole (1), was selected for clinical studies.