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Upstream product

• 75319-92-5 2-(2'-hydroxyethyl)-4-acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one 
• 112-76-5 Stearoyl chloride 

Relevant academic research and scientific papers

Antihypertensive pyridazin(2H)-3-ones

Compounds of the formula STR1 are useful antihypertensive agents.

Lipophilic and hydrophilic esters of 4-acetyl-2-(2-hydroxyethyl)-5,6-bis (4-chlorophenyl)2h-pyridazin-3-one as antihypertensive agents

In an attempt to enhance the antihypertensive activity of 4-acetyl-2-(2-hydroxyethyl)-5,6-bis(4-chlorophenyl)-2H-pyridazin-3-one, (1), a series of lipophilic and hydrophilic esters was synthesized. These derivatives possessed increased lipid and aqueous s