75319-92-5

Usage

InChI:InChI=1/C20H16Cl2N2O3/c1-12(26)17-18(13-2-6-15(21)7-3-13)19(14-4-8-16(22)9-5-14)23-24(10-11-25)20(17)27/h2-9,25H,10-11H2,1H3

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 75643-31-1 4-Acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one 
• 40036-75-7 (E)-4,4'-dichlorobenzil monohydrazone 

Downstream Products

• 75320-03-5 tert-Butoxycarbonylamino-acetic acid 2-[5-acetyl-3,4-bis-(4-chloro-phenyl)-6-oxo-6H-pyridazin-1-yl]-ethyl ester 
• 75320-02-4 2-[4'-acetyl-5',6'-bis(p-chlorophenyl)-pyridazin-3'-one-2'-yl]ethyl (N-benzyloxycarbonyl)-β-alaninate 
• 75319-99-2 Benzyloxycarbonylamino-acetic acid 2-[5-acetyl-3,4-bis-(4-chloro-phenyl)-6-oxo-6H-pyridazin-1-yl]-ethyl ester 
• 75333-84-5 2-Benzyloxycarbonylamino-3-methyl-butyric acid 2-[5-acetyl-3,4-bis-(4-chloro-phenyl)-6-oxo-6H-pyridazin-1-yl]-ethyl ester 
• 75320-00-2 C₃₄H₃₃Cl₂N₇O₈ 
• 75319-93-6 2-[4'-acetyl-5',6'-bis(p-chlorophenyl)-pyridazin-3'-one-2'-yl]ethyl pivalate 
• 75319-97-0 2-[4'-acetyl-5',6'-bis(p-chlorophenyl)-pyridazin-3'-one-2'-yl]ethyl benzoate 
• 75320-01-3 2-Benzyloxycarbonylamino-3-phenyl-propionic acid 2-[5-acetyl-3,4-bis-(4-chloro-phenyl)-6-oxo-6H-pyridazin-1-yl]-ethyl ester 
• 75319-95-8 Isobutyric acid 2-[5-acetyl-3,4-bis-(4-chloro-phenyl)-6-oxo-6H-pyridazin-1-yl]-ethyl ester 
• 75319-96-9 2-[4'-acetyl-5',6'-bis(p-chlorophenyl)-pyridazin-3'-one-2'-yl]ethyl octadecanoate 
• 75319-98-1 Phenyl-acetic acid 2-[5-acetyl-3,4-bis-(4-chloro-phenyl)-6-oxo-6H-pyridazin-1-yl]-ethyl ester 
• 75644-12-1 2-[2'-(1-pyrrolidinyl)ethyl]-4-acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one 
• 75644-10-9 2-[2'-(1-piperidinyl)ethyl]-4-acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one 
• 75644-08-5 4-Acetyl-5,6-bis-(4-chloro-phenyl)-2-(2-morpholin-4-yl-ethyl)-2H-pyridazin-3-one 

Relevant academic research and scientific papers

Isolation and identification of impurities in 4-acetyl-2-(2'-hydroxyethyl)-5,6-bis (4-chlorophenyl)- 2H-pyridazin-3-one, an antihypertensive agent

Three trace impurities found in 4-acetyl-2-(2'-hydroxyethyl)-5,6-bis(4-chlorophenyl)-2H-pyridazin-3-one (II), a novel antihypertensive agent, were isolated by a combination of low-pressure liquid chromatography and preparative TLC. These impurities were i

Antihypertensive 5,6-diarylpyridazin-3-ones

The synthesis of a series of 5,6-diarylpyridazinones is described. Some members of this series display an antihypertensive effect in both the spontaneously hypertensive rat model and the deoxycorticosteroid (DOCA) model of hypertension. The most potent co

Antihypertensive pyridazin(2H)-3-ones

Compounds of the formula STR1 are useful antihypertensive agents.