75321-72-1Relevant academic research and scientific papers
Titanium(IV) Chloride-Mediated Stereoselective α-Alkylidenation to Efficiently Assemble Multisubstituted 1,3-Dienes
Sun, Rengwei,Song, Wei,Ma, Chunmei,Zhang, Huiwen,Yu, Xinhong
supporting information, p. 3977 - 3982 (2016/12/30)
A direct access to multisubstituted 1,3-dienes by α-exclusive alkylidenation of crotonic derivatives has been developed. This protocol, mediated by titanium tetrachloride chelation, features excellent regio- and stereoselectivity, mild reaction conditions, easy operation and wide substrate scope. Conversions of the derived dienes to other useful molecules were also explored. (Figure presented.).
Development of general methods for the synthesis of new substituted allyl bromides as promising alkenylating agents
Moskalenko,Boev
, p. 953 - 959 (2014/10/16)
A general procedure has been developed for the synthesis of hitherto unknown substituted allyl bromides. The procedure includes preparation of the corresponding α,β-unsaturated carboxylic acid esters from accessible ketones according to the Horner-Emmons
Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring
Mirzabekova,Kuz'mina,Lukashov,Sokolova,Golosov,Kazakov,Perlova,Potapova,Kheinman,Ivanova
experimental part, p. 1139 - 1149 (2009/09/25)
A number of permethrinic acid ethyl ester derivatives having various substituents [Et, Pr, Ph, Ph(CH2) n (n = 1, 2), etc.] in position 2 of the cyclopropane ring were synthesized, and their insecticidal acivity against typhoid flies, rice weevils, and bean aphides, as well as juvenoid activity on flour beetle chrysalises, was studied. The newly synthesized compounds turned out to exhibit weak insecticidal activity against standard insects but pronounced juvenile hormone activity, which differentiates them from permethrinic acid esters.
TMSCl-mediated catalytic carbocupration of alkynoates: An unprecedented and remarkable effect of catalyst loading on highly selective stereochemical induction via a TMS-allenoate intermediate
Jennings, Michael P.,Sawant, Kailas B.
, p. 3201 - 3204 (2007/10/03)
The TMSCl-mediated catalytic carbocupration of alkynoates has been investigated. It has been shown that catalyst loadings as low as 30 mol% readily allow for high yields and diastereoselectivities for a series of Grignard reagents. In addition, an unprecedented and remarkable effect of catalyst loading on stereochemical induction has been observed. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).
Thioepoxide formation by ring closure of allylthiyl radicals - A novel rearrangement of allylic thionitrites
Cavero, Marta,Motherwell, William B.,Potier, Pierre,Weibel, Jean-Marc
, p. 2394 - 2395 (2007/10/03)
Tertiary allylic thionitrites undergo thermal rearrangement to α,β-episulfide nitroso dimers via ring closure of allylthiyl radicals.
Carbon-Carbon Bond Formation at the γ-position of Dienolates via the Palladium Catalysed Coupling of the Tin Masked Dienolates
Yamamoto, Yoshiri,Hatsuya, Satoshi,Yamada, Jun-ichi
, p. 86 - 87 (2007/10/02)
The palladium catalysed coupling reaction of the tin masked dienolate (2) with organic halides takes place at the position substituted by tin, thereby providing a new method for C-C bond formation at the γ-position of dienolates.
