75326-24-8

Upstream product

• 82897-94-7 (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide 
• 37924-67-7 α-bromo-1,2-benzisoxazole-3-acetic acid 
• 82897-91-4 (1,2-benzisoxazol-3-yl)(phenylthio)acetic acid 
• 82897-92-5 3-Phenylsulfanylmethyl-benzo[d]isoxazole 
• 930-69-8 sodium thiophenolate 
• 81981-84-2 C₁₄H₁₁ClN₂O₂S 
• 75326-37-3 N-bromo-S-phenyl-S<(1,2-benzisoxazol-3-yl)methyl>sulfoximide 

Downstream Products

• 75326-34-0 C₁₄H₁₁ClN₂O₂S 
• 81981-84-2 C₁₄H₁₁ClN₂O₂S 
• 75326-37-3 N-bromo-S-phenyl-S<(1,2-benzisoxazol-3-yl)methyl>sulfoximide 
• 75326-29-3 C₁₄H₁₁BrN₂O₂S 

Relevant academic research and scientific papers

Novel Rearrangements of N- and α-Halogeno-derivatives of S-Aryl-S-sulphoximides to the Corresponding N-Sulphinylimines

The title N- and α-halogeno-sulphoximides (1) and (2) undergo base-induced rearrangement reactions to give the corresponding N-sulphinylimines (3), suggesting the intermediacy of a three-membered cyclic sulphoximide (4) with an endocyclic S=N moiety.

Halogenation Reaction of S-Aryl-Ssulfoximide

The reactions of the title free sulfoximide with N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS) afforded the corresponding α-halogenated "free" sulfoximides in good yields.The α-bromination proceeded via a facile N-bromination followed by a bromine transfer reaction of the resulting N-bromosulfoximide.The NCS chlorination, in contrast, proceeded via direct α-chlorination, not via N-chlorination.However, in the presence of potassium carbonate or silica gel N-chlorination occured predominantly in the NCS chlorination.Keywords---1,2-benzisoxazole; halogenation; N-halosulfoximide; α-halo sulfoximide; rearrangement; induction period

Rearrangement reaction of N-halo-s-[(1,2-benzisoxazol-3-yl)methyl]-sulfoximine to the corresponding α-halo sulfoximine

The first example of the rearrangement reaction of N-halosulfoximine to α-halo sulfoximine is described.