753456-21-2

Basic information

• Product Name: N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-levulinyl-2'-deoxycytidine
• Synonyms: N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-levulinyl-2'-deoxycytidine
• CAS NO: 753456-21-2
• Molecular Weight: 616.692
• Mol File: 753456-21-2.mol

Chemical Properties

• CAS DataBase Reference: N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-levulinyl-2'-deoxycytidine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-levulinyl-2'-deoxycytidine(753456-21-2)
• EPA Substance Registry System: N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-levulinyl-2'-deoxycytidine(753456-21-2)

Safety Data

• Hazardous Substances Data: 753456-21-2(Hazardous Substances Data)

Upstream product

• 5167-85-1 2,2,5,5-tetramethyl-3-oxopyrrolidine 
• 91592-66-4 N-benzoyl-3'-O-levulinoyl-2'-deoxy-β-D-cytidine 
• 67219-55-0 4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine 
• 123-76-2 levulinic acid 
• 93134-38-4 (2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl-4-oxopentanoate 
• 19805-75-5 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide 

Downstream Products

• 753456-29-0 N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-3'-O-[(N,N-diisopropylamino)(2-cyanoethyloxy)]phosphinyl-2'-deoxycytidine 
• 753456-25-6 N⁴-benzoyl-5'-O-(2,2,5,5-tetramethylpyrrolidin-3-one-1-sulfinyl)-2'-deoxycytidine 

Relevant articles and documents

2,2,5,5-Tetramethylpyrrolidin-3-one-1-sulfinyl group for 5′-hydroxyl protection of deoxyribonucleoside phosphoramidites in the solid-phase preparation of DNA oligonucleotides

Several nitrogen-sulfur reagents have been investigated as potential 5′-hydroxyl protecting groups for deoxyribonucleoside phosphoramidites to improve the synthesis of oligonucleotides on glass microarrays. Out of the nitrogen-sulfur-based protecting grou