753471-77-1

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 108-94-1 cyclohexanone 
• 7524-52-9 (S)-tryptophan methyl ester hydrochloride 

Downstream Products

• 753471-79-3 C₁₉H₂₃N₃O₂ 
• 753471-81-7 N-(1-carbamoylcyclohexyl)-L-tryptophan methyl ester 
• 951243-22-4 methyl (2S,3aR,8aS)-1-(1-cyanocyclohexyl)-3a-(methylthiomethyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-2-yl-carboxylate 
• 852060-16-3 [2-(1H-indol-3-ylmethyl)-3,5-dioxo-1,4-diaza-spiro[5.5]undec-4-yl]-acetic acid benzyl ester 

Relevant academic research and scientific papers

Molecular diversity via amino acid derived α-amino nitriles: Synthesis of spirocyclic 2,6-dioxopiperazine derivatives

(Chemical Equation Presented) Chiral spirocyclic 2,6-dioxopiperazines were synthesized from amino acid derived α-quaternary α-amino nitriles via H2SO4-promoted cyano hydration, followed by base-mediated cyclization and N-alkylation.

Unprecedented stereospecific synthesis of a novel tetracyclic ring system, a hybrid of tetrahydropyrrolo[2,3-b]indole and tetrahydroimidazo[1,2-a]indole, via a domino reaction upon a tryptophan-derived amino nitrile

Compounds containing a novel tetracyclic ring system, a hybrid of tetrahydropyrrolo[2,3-b]indole and tetrahydroimidazo[1,2-a]indole, are synthesized via an acid-mediated stereospecific domino tautomerization of a tryptophan-derived α-amino nitrile. Charac