753491-58-6

Basic information

• Product Name: 4-(2-oxo-3-phenyl-imidazolidin-1-yl)-benzoic acid ethyl ester
• CAS NO: 753491-58-6
• Molecular Weight: 310.353
• Mol File: 753491-58-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-oxo-3-phenyl-imidazolidin-1-yl)-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-oxo-3-phenyl-imidazolidin-1-yl)-benzoic acid ethyl ester(753491-58-6)
• EPA Substance Registry System: 4-(2-oxo-3-phenyl-imidazolidin-1-yl)-benzoic acid ethyl ester(753491-58-6)

Safety Data

• Hazardous Substances Data: 753491-58-6(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 699-11-6 N-phenyl-2-bromoethylamine 
• 753491-50-8 4-[3-(2-bromo-ethyl)-3-phenyl-ureido]-benzoic acid ethyl ester 

Relevant articles and documents

Design and synthesis of cyclic urea compounds: A pharmacological study for retinoidal activity

Retinoids are natural and synthetic analogues of all-trans retinoic acid (ATRA). Cancer and other serious hyperproliferative diseases are attractive therapeutic targets for retinoids. We report here the design and synthesis of novel cyclic urea compounds with retinoidal activity. YR105 exhibited potent differentiation-inducing ability toward human promyelocytic leukemia HL-60 cells at the concentration of 10-9M: its potency was almost equal to that of the native ligand, all-trans retinoic acid.