753498-13-4Relevant academic research and scientific papers
A simple route to side-chain fluorinated β-lactams from ring-fluorinated aziridines
Konev, Alexander S.,Novikov, Mikhail S.,Khlebnikov, Alexander F.,Tehrani, Kourosch Abbaspour
, p. 114 - 119 (2008/03/13)
β-Lactams bearing a Ph2CF substituent at the C(4)-atom were synthesized from N-alkyl-2-fluoro-3,3-diphenylaziridines. The transformation was realized using SbF3-mediated isomerization of the monofluoroaziridines to fluorinated aldimines, followed by Staudinger reaction with ketenes. It was shown that this reaction sequence can be performed as a one-pot procedure.
Controlled submolecular translational motion in synthesis: A mechanically interlocking auxiliary
Hannam, Jeffrey S.,Lacy, Stephen M.,Leigh, David A.,Saiz, Carlos G.,Slawin, Alexandra M. Z.,Stitchell, Sheila G.
, p. 3260 - 3264 (2007/10/03)
Sew simple: How can you put a molecular bead on a thread when no recognition elements exist between them? A mechanically interlocking auxiliary assembles the macrocycle around a template, controlled submolecular translation moves the ring over the desired
