7535-15-1

Basic information

• Product Name: [1,1'-BIPHENYL]-2,2'-DICARBONYL DICHLORIDE
• Synonyms: [1,1'-BIPHENYL]-2,2'-DICARBONYL DICHLORIDE
• CAS NO: 7535-15-1
• Molecular Formula: C₁₄H₈Cl₂O₂
• Molecular Weight: 279.121
• Mol File: 7535-15-1.mol

Chemical Properties

• Boiling Point: 428.9±38.0 °C(Predicted)
• Appearance: /
• Density: 1.344±0.06 g/cm3(Predicted)
• CAS DataBase Reference: [1,1'-BIPHENYL]-2,2'-DICARBONYL DICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-BIPHENYL]-2,2'-DICARBONYL DICHLORIDE(7535-15-1)
• EPA Substance Registry System: [1,1'-BIPHENYL]-2,2'-DICARBONYL DICHLORIDE(7535-15-1)

Safety Data

• Hazardous Substances Data: 7535-15-1(Hazardous Substances Data)

Upstream product

• 863305-32-2 diphenic acid 
• 118-92-3 anthranilic acid 
• 6050-13-1 biphenyl-2,2'-dicarboxylic acid anhydride 

Downstream Products

• 18076-62-5 2,2'-bis(hydroxyldiphenylmethyl)biphenyl 
• 20837-34-7 2,2'-bis(4-methoxybenzoyl)biphenyl 
• 115963-82-1 2,2'-Bis-(2,4-dimethyl-benzoyl)-biphenyl 
• 103326-20-1 2,2'-Bis-(2,4,6-trimethyl-benzoyl)-biphenyl 
• 51439-35-1 S,S-bis(p-methylphenyl) diphenthioate 
• 110926-83-5 N,N,N',N'-tetracyclohexyl-2,2'-biphenyldicarboxamide 
• 103162-57-8 [1,1'-biphenyl]-2,2'-diylbis(p-tolylmethanone) 
• 214851-72-6 4-benzoyl-9H-fluoren-9-one 
• 6223-83-2 9-oxo-9H-fluorene-4-carboxylic acid 

Relevant articles and documents

Thermodynamic and structural investigations on the complexation process of dioxo macrocyclic ligands: towards neutral copper complexes at Physiological pH

Two dioxotetraza macrocycles 9,12,16,19-tetraazatricyclo[19.4.0.0 2'7]pentacosa-l(21),2,4,6,22,24-hexaene-8,20-dione (L1) and 9,13,16,20-tetraazatricyclo[20.4.0.02,7]hexacosa1(22),2,4,6,23, 25-hexaene-8,21-dione (L2) and two bis(dioxotetraaza) macrocycles 7,10,14,17,25,28,32,35-octaazatetracyclo[17.17,2.05,37.0 23'38]octatriaconta-l,3,5(37), 19,21,23(38)hexaene-6,18,24,36-tetrone (L3) and 7,11,14,18,26,30,33,37octaazatetracyclo[18.18.2.0 5,39.024,40]tetracontal,3,5(39),20,22,24(40)-hexaene-6,19, 25,38-tetrone (L4) were prepared, Their protonation constants and the overall complexation constants of their copper(II) complexes were determined by potentiometry at 25 °C (I = I, KNO3), In aqueous solution, the complexation sequence was elucidated for each ligand by means of UV/Vis and EPR spectroscopy. According to the ligand structure, two coniplexation mechanisms can be characterized, For ligand L1, a neutral complex [CuL1I-L2] is readily obtained in one step at: pH 5, and it is the sole species above pH 7, Its structure was confirmed by X-ray analysis, For ligands L2 and L4, the neutral complexes [CuL2FL-2] and [Cu2L4FLi] were formed by successive deprotonation of [Cu.L2]2+ and [Cu2L4]4+, respectively,

Delicate modulated assembly of a new kind of trinuclear copper(II) motif governed by N-containing agents

A new kind of trinuclear copper(ii) motif [Cu3L] was prepared in situ by adopting a multidentate ligand, N′2,N′2′-bis(2-hydroxybenzoyl)biphenyl-2,2′-dicarbohydrazide (H6L), in the presence of a series N-containing agents. Featuring five different assembly styles, [Cu3L(DMF)2.5(hmta)]·3H2O (1), [Cu3L(DMA)(H2O)(Hmor)] (2), [Cu3L(py)2]·DMF (3), [Cu3L(DMF)(H2O)]·2DMF (4), and [Cu3L(DMA)(H2O)]·0.5DMA (5) (hmta = hexamethylenetetramine, Hmor = morphiline, py = pyridine) were obtained. In these assemblies, the [Cu3L] units are connected with each other into one-dimensional chains via bridging of N-containing agents or via sharing an oxygen atom of L6- to fuse together. Furthermore, the connecting styles are found to be governed by the character of the N-containing agents used, which is discussed in detail. Thermal gravimetric analysis and magnetic measurement of some complexes were performed.

COMPOUNDS TARGETING ALPHA4-BETA7 1NTEGRIN

Compounds of formula (I) and pharmaceutically acceptable salts and solvates thereof, are described. The compounds are α4β7 antagonists and are useful in the prevention or treatment of inflammatory conditions and/or autoimmune diseases, especially inflamma

Cobalt-Bisoxazoline-Catalyzed Enantioselective Cross-Coupling of α-Bromo Esters with Alkenyl Grignard Reagents

The first catalytic asymmetric Kumada cross-coupling of organic halides with alkenyl Grignard reagents has been developed. The reaction was promoted by the cobalt-bisoxazoline catalyst and afforded various α-alkyl-β,γ-unsaturated esters with excellent enantioselectivities and moderate to good yields (≤95% ee and ≤82% yields). The formal synthesis of the California red scale pheromone using this method was investigated, and radical clock experiments were performed.

Preparation method of 2,2'-biphenyldicarboxylic acid diallylester

The invention provides a preparation method of 2,2'-biphenyldicarboxylic acid diallylester. The method comprises the following steps: step 1, mixing thionyl chloride with 2,2'-biphenyldicarboxylic acid at the mole ratio of (4 to 5) to 1, adding a catalyst, heating at the temperature of 100-120 DEG C and carrying out reflux reaction for 3-12 hours; step 2, mixing 2,2'-biphenyldicarbonyl chloride prepared in step 1 and allyl alcohol at the mole ratio of 1 to (2 to 3), heating to 100-110 DEG C, carrying out reflux reaction for 4-8 hours, washing until the pH of an aqueous phase is 6, and adding anhydrous magnesium sulfate for drying an organic layer; step 3, adding a polymerization inhibitor into an organic phase prepared by step 2, performing reduced pressure distillation for 1-5 hours to obtain a finished product of 2,2'-biphenyldicarboxylic acid diallylester. The catalyst is one or a combination of any two of N,N'-dimethylformamide and pyridine. The polymerization inhibitor is one of copper powder, cuprous chloride and hydroquinone.

Ruthenium-Catalyzed Reductive Cleavage of Unstrained Aryl-Aryl Bonds: Reaction Development and Mechanistic Study

Cleavage of carbon-carbon bonds has been found in some important industrial processes, for example, petroleum cracking, and has inspired development of numerous synthetic methods. However, nonpolar unstrained C(aryl)-C(aryl) bonds remain one of the toughest bonds to be activated. As a detailed study of a fundamental reaction mode, here a full story is described about our development of a Ru-catalyzed reductive cleavage of unstrained C(aryl)-C(aryl) bonds. A wide range of biaryl compounds that contain directing groups (DGs) at 2,2′ positions can serve as effective substrates. Various heterocycles, such as pyridine, quinoline, pyrimidine, and pyrazole, can be employed as DGs. Besides hydrogen gas, other reagents, such as Hantzsch ester, silanes, and alcohols, can be employed as terminal reductants. The reaction is pH neutral and free of oxidants; thus a number of functional groups are tolerated. Notably, a one-pot C-C activation/C-C coupling has been realized. Computational and experimental mechanistic studies indicate that the reaction involves a ruthenium(II) monohydride-mediated C(aryl)-C(aryl) activation and the resting state of the catalyst is a η4-coordinated ruthenium(II) dichloride complex, which could inspire development of other transformations based on this reaction mode.

HIGH GLASS TRANSITION TEMPERATURE "MEDIUM-SIZED" AMBIPOLAR HOST MATERIALS

Disclosed herein are am bipolar host compounds represented by formula (I), wherein: a) R4 is an optionally substituted aryl or an optionally substituted heteroaryl group; b) n is at least 2; e) for each (ii) at least one of R1, R2 and R3 is independently an optionally substituted carbazole group, and the remaining of R1, R2 and R3 are independently selected from hydrogen, halogen and a C1-20 organic group: and d ) Y is selected from (III), wherein R5 is an.optionally substituted aryl group, an optionally substituted heteroaryl group, an optionally substituted alkyl group or an optionally substituted heteroalkyl group, and wherein R6 is hydrogen,, an optionally substituted aryl group, an optionally substituted heteroaryl group, an optionally substituted alkyl -group or an optionally substituted heteroalky! group. The compounds can be used in OLED devices and are ambipolar. The OLED devices can show high efficiency and high luminance.

Novel benzimidazole derivatives as electron-transporting type host to achieve highly efficient sky-blue Phosphorescent organic light-emitting diode (PHOLED) device

The development of benzimidazole substituted biphenyls as electron-transporting hosts for bis[2-(4,6-difluorophenyl)pyridinato-C2,N](picolinato)iridium-(III) is reported. Under the optimized conditions, the organic light-emitting diode (OLED) a

Chiral bisoxazoline ligands with a biphenyl backbone: Development and application in catalytic asymmetric allylic oxidation of cycloolefins

A simple and efficient method for the synthesis of chiral biphenylbisoxazoline ligands was developed. The bishydroxylamide precursors of ligands showed a dynamic atropselective resolution effect in the crystallization process. When biphenylbisoxazoline ligands were coordinated to tetrakis(acetonitrile)copper(I) hexafluorophosphate, it resulted in the formation of only a single diastereomer complex (S,aS,S), which behaved as a catalyst for the enantioselective allylic oxidation of cycloolefins. The enantioselectivity, yield, and rate of this reaction were optimized under different conditions, such as a change of solvents, temperature, and additives and also using various copper salts. The use of SBA-15 mesoporous silica as an additive played a crucial role in increasing the efficiency of the reaction.

Novel biphenyl organocatalysts for iminium ion-catalyzed asymmetric epoxidation

Two novel chiral biphenyl iminium salts derived from L-acetonamine, containing electron-withdrawing 3,30-substituents on the biphenyl unit, have been prepared and tested as asymmetric catalysts for epoxidation of prochiral alkenes. The results are compared with those achieved using the corresponding unsubstituted system.