75350-46-8

Basic information

• Product Name: FLUORESCEIN-5-MALEIMIDE
• Synonyms: FLUORESCEIN-5-MALEIMIDE;5-Maleimido-fluorescein;N-(5-Fluoresceinyl)maleimide;1-(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-1H-pyrrole-2,5-dione;1-(3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione;5-MF [Fluorescein-5-MaleiMide];5-Maleimido-fluorescein;5-MF
• CAS NO: 75350-46-8
• Molecular Formula: C₂₄H₁₃NO₇
• Molecular Weight: 427.36
• Product Categories: Fluorescent Labels and Indicators;Fluorescent Labels & Indicators;Maleimide Derivatives;MTS & Sulfhydryl Active Reagents
• Mol File: 75350-46-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: >275°C (dec.)
• Boiling Point: 769.1 °C at 760 mmHg
• Flash Point: 418.9 °C
• Appearance: /
• Density: 1.73 g/cm³
• Storage Temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 9.31±0.20(Predicted)
• CAS DataBase Reference: FLUORESCEIN-5-MALEIMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: FLUORESCEIN-5-MALEIMIDE(75350-46-8)
• EPA Substance Registry System: FLUORESCEIN-5-MALEIMIDE(75350-46-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 75350-46-8(Hazardous Substances Data)

Usage

Uses

Fluorescein-5-maleimide is the most widely used green fluorescent thiol-reactive dye. The reaction requires very mild condition and is highly specific.

Upstream product

• 3326-34-9 fluoresceinamine 

Relevant articles and documents

Efficient synthesis of fluorophore-linked maleimide derivatives

Lewis acid and hexamethyldisilazane promoted efficient synthesis of various fluorophore-linked maleimide derivatives from maleic anhydride and amines is described.