75359-71-6Relevant academic research and scientific papers
Primary-amine-catalyzed enantioselective intramolecular aldolizations
Zhou, Jian,Wakchaure, Vijay,Kraft, Philip,List, Benjamin
supporting information; experimental part, p. 7656 - 7658 (2009/04/10)
Aldol cyclodehydration of 4-substituted-2,6-heptanediones leads to enantiomerically enriched 5-substituted-3-methyl-2-cyclohexene-1-ones, which serve as perfume ingredients and valuable synthetic building blocks.Primary amines derived from cinchona alkalo
A continuous Michael and aldol coupling of α,β-enones catalyzed by iridium complexes
Matsuda, Isamu,Makino, Tatsuya,Hasegawa, Yuki,Itoh, Kenji
, p. 1409 - 1412 (2007/10/03)
Ir[(COD)(PPh3)2]OTf activated by H2 molecule catalyzes Michael-type coupling of α,β-enones with enoxysilanes to give 1,5-dicarbonyl compounds after the subsequent protodesilylation. An identical catalyst system makes it possible to attain a continuous Michael and aldol modification toward α,β- enones in a one-pot operation. (C) 2000 Elsevier Science Ltd.
Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2.
List,Lerner,Barbas 3rd.
, p. 59 - 61 (2008/02/11)
[formula: see text] Aldolase antibody 38C2 catalyzes the enantioselective aldol cyclodehydration of 4-substituted-2,6-heptanediones (3) to give enantiomerically enriched 5-substituted-3-methyl-2-cyclohexen-1-ones (4). Yields, enantioselectivities, and pro
LATENT ACETONYLATION OF α,β-ENONES WITH ALLYLTRIMETHYLSILANE OR 2-METHYL-2-PROPENYLTRIMETHYLSILANE: SYNTHESIS OF 1,5-DIKETONES AND ANNELATION TO FUSED CYCLOHEXENONES
Hosomi, Akira,Kobayashi, Hiroshi,Sakurai, Hideki
, p. 955 - 958 (2007/10/02)
Acetonylation of α,β-enones can be achieved by either with (2-methyl-2-propenyl)trimethylsilane or with allyltrimethylsilane followed by oxidative cleavage of the double bond or by the Wacker reaction, respectively.Annelation of the 1,5-diketones is also
