75373-35-2

Upstream product

• 10544-63-5 ethyl crotonate 
• 117083-18-8 {[1-Phenyl-eth-(Z)-ylideneamino]-methyl}-phosphonic acid diethyl ester 
• 75373-44-3 (2S,3R,4R)-2,4-Dimethyl-2-phenyl-3,4-dihydro-2H-pyrrole-3-carboxylic acid ethyl ester 
• 762-04-9 phosphonic acid diethyl ester 
• 75373-35-2 (2R,3S,4S,5R)-5-(Diethoxy-phosphoryl)-2,4-dimethyl-2-phenyl-pyrrolidine-3-carboxylic acid ethyl ester 
• 75373-45-4 (2S,3R,4R)-2,4-Dimethyl-2-phenyl-3,4-dihydro-2H-pyrrole-3-carboxylic acid ethyl ester; compound with picric acid 

Downstream Products

• 75373-35-2 (2R,3R,4S,5R)-5-(Diethoxy-phosphoryl)-2,4-dimethyl-2-phenyl-pyrrolidine-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

α-Aminophosphonates. III. Cycloaddition anionique-1,3 des esters α,β-insatures: Preparation et transformations des Δ1-pyrrolines

The anions of the 2-azaallylphosphonates 1 react with the α,β-unsaturated esters 2 to yield intermediates 4'.These intermediates form the 2-diethoxyphosphonyl-4-ethoxycarbonylpyrrolidines 4 following a protonation while an elimination of the anion of the

ANIONS LITHIENS DERIVES D'AZA-2 ALLYLPHOSPHONATES. SYNTHESE REGIO ET STEREOSPECIFIQUE DE NOUVELLES δ1-PYRROLINES

Novel δ1-pyrrolins are obtained by the 1,3-cycloaddition of lithio-anions derived from 2-aza-allylphosphonates on actived double bonds; phosphite is then eliminated.