75409-90-4

Basic information

• Product Name: 2-benzyl-3-oxo-2-azabicyclo<2.2.1>hept-6-exo-yl p-toluenesulfonate
• Synonyms: 2-benzyl-3-oxo-2-azabicyclo<2.2.1>hept-6-exo-yl p-toluenesulfonate
• CAS NO: 75409-90-4
• Molecular Weight: 371.457
• Mol File: 75409-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyl-3-oxo-2-azabicyclo<2.2.1>hept-6-exo-yl p-toluenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-3-oxo-2-azabicyclo<2.2.1>hept-6-exo-yl p-toluenesulfonate(75409-90-4)
• EPA Substance Registry System: 2-benzyl-3-oxo-2-azabicyclo<2.2.1>hept-6-exo-yl p-toluenesulfonate(75409-90-4)

Safety Data

• Hazardous Substances Data: 75409-90-4(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 38318-60-4 2-benzyl-3-oxo-6-exo-hydroxy-2-azabicyclo<2.2.1>heptane 

Downstream Products

• 78805-81-9 2-benzyl-3-oxo-2-azabicyclo<2.2.1>heptane 
• 78805-80-8 2-benzyl-2-azabicyclo[2.2.1]hept-5-en-3-one 

Relevant articles and documents

Synthesis of Diphenyl Ether Models of Thyroid Hormones. Diphenyl Ethers Linked to the 3-Oxo-2-azabicycloheptane Ring System as Substrates for Conformational Analysis

A series of diphenyl ethers linked to 2-azabicyclooctan-3-ones and 2-azabicycloheptan-3-ones were synthesized as substrates for conformational analysis using the lanthanide shift reagent NMR technique.The materials were prepared by displacement of the exo-6-tosyloxy bicyclic lactam with the corresponding phenoxide which results in formation of the phenyl ether with retention of stereochemistry.This double-inversion process presumably involves anchimeric assistance by the lactam nitrogen.The synthesis and properties of a number of these systems are described.Complete 13C assignments for the series are presented.