7541-06-2

Basic information

• Product Name: (4-chlorophenyl)<(Z)-hydroxyimino>acetonitrile
• Synonyms: (4-chlorophenyl)<(Z)-hydroxyimino>acetonitrile
• CAS NO: 7541-06-2
• Molecular Weight: 180.593
• Mol File: 7541-06-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4-chlorophenyl)<(Z)-hydroxyimino>acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)<(Z)-hydroxyimino>acetonitrile(7541-06-2)
• EPA Substance Registry System: (4-chlorophenyl)<(Z)-hydroxyimino>acetonitrile(7541-06-2)

Safety Data

• Hazardous Substances Data: 7541-06-2(Hazardous Substances Data)

Upstream product

• 1073-67-2 4-vinylbenzyl chloride 
• 140-53-4 p-chlorobenzyl cyanide 
• 151-50-8 potassium cyanide 
• 74903-80-3 (Z)-N-hydroxy-4-chloro-benzenecarboximidoyl chloride 
• 1940-57-4 9H-fluoren-9-yl bromide 
• 107960-25-8 C₈H₄ClN₂O₂^(1-)*Ag⁽¹⁺⁾ 

Downstream Products

• 21741-98-0 3-amino-4-(p-chlorophenyl)-1,2,5-oxadiazole 

Relevant articles and documents

Visible-Light-Induced Difunctionalization of Styrenes: Synthesis of N-Hydroxybenzimidoyl Cyanides

A visible-light-induced synthesis of N-hydroxybenzimidoyl cyanides from aromatic terminal alkenes is achieved by using Eosin Y as an organic photoredox catalyst. The process goes via a radical pathway with successive incorporation of two nitrogen atoms, one each from tert-butyl nitrite and ammonium acetate. The final product is achieved by the concomitant installation of an oxime and a nitrile group. DFT calculation supports a biradical pathway and all the proposed steps. A few useful synthetic transformations of N-hydroxybenzimidoyl cyanide are also illustrated.

AGENT FOR PREVENTION AND TREATMENT OF CANCER COMPRISING OXADIAZOLE UREA COMPOUND OBSTRUCTING ACTIVITY OF STAT

Disclosed herein is an agent for preventing and treating cancer comprising an oxadiazole urea compound represented by Chemical Formula 1, below, as an effective ingredient. The oxadiazole urea compound effectively inhibits the growth of cancer cell lines

Reaction of the Silver Salts of Arylnitroacetonitriles with 9-Bromofluorene. Synthesis of 9-(α-Cyanoarylidene)fluorenes

The silver salts 1a-d react with 9-bromofluorene to give both C- and O-alkylated products 2 and 3.The latter decompose to yield 9-fluorenone and the α-cyanooximes 5.The products 2 upon treatment with NaOH/EtOH eliminate HNO2 to afford 9-(α-cyanoarylidene)fluorenes 4 in 80percent yield. 9-Chloro-9-phenylfluorene reacts with salt 1a to give only C-alkylated product 6 in 70percent yield.