21741-98-0

Upstream product

• 13014-48-7 4-chlorobenzoyl cyanide 
• 22027-53-8 methyl 3-(4-chlorophenyl)-3-oxopropanoate 
• 104-88-1 4-chlorobenzaldehyde 
• 28123-63-9 4-chlorobenzohydroximoyl chloride 
• 4236-13-9 p-chloro-2-(hydroxyimino)-2-phenylacetonitrile 
• 7541-06-2 (4-chlorophenyl)<(Z)-hydroxyimino>acetonitrile 
• 3750-07-0 2-(4-chlorophenyl)-2-oxoacetaldehyde oxime 

Downstream Products

• 49615-82-9 {[4-(4-chloro-phenyl)-furazan-3-ylamino]-methylene}-malonic acid diethyl ester 
• 114854-41-0 N-(p-tolyl)-N'-<4-(p-chlorophenyl)-1,2,5-oxadiazol-3-yl>thiourea 
• 106446-21-3 3-(4-chlorophenyl)-4-triphenylphosphiniminofurazan 
• 106446-20-2 3-(4-chlorophenyl)-4-trioctylphosphiniminofurazan 
• 106446-22-4 3-(4-chlorophenyl)-4-nitrofurazan 
• 106446-23-5 azoxy(4-chlorophenylfurazan) 
• 96594-50-2 C₁₆H₁₀ClF₃N₄O₂ 
• 1374224-11-9 2-chloro-N-[4-(4-chlorophenyl)-1,2,5-oxadiazol-3-yl]-4-(methylsulfonyl)benzamide 
• 106466-53-9 3-(4-chlorophenyl)-4-dimethylsulfiliminofurazan 

Relevant academic research and scientific papers

N -Oxide-Controlled Chemoselective Reduction of Nitrofuroxans

A facile and chemoselective SnCl 2 -mediated mild reduction of regioisomeric 3- and 4-nitrofuroxans for the synthesis of aminofurazans and aminofuroxans in good yields is developed. Reduction of 4-nitrofuroxans results in the selective formation of 4-aminofuroxans, while analogous reduction of 3-nitrofuroxans affords 3-aminofurazans as a result of simultaneous reduction of the nitro group and exocyclic N-O bond.

Mild Synthesis of Substituted 1,2,5-Oxadiazoles Using 1,1′-Carbonyldiimidazole as a Dehydrating Agent

1,1′-Carbonyldiimidazole was found to induce the formation of a variety of 3,4-disubstituted 1,2,5-oxadiazoles (furazans) from the corresponding bisoximes at ambient temperature. This method enables these inherently energetic compounds to be prepared at t

Synthesis of new dithiolethione and methanethiosulfonate systems endowed with pharmaceutical interest

Here we report synthetic methodology affording in the most efficient way the rapid preparation of new dithiolethiones (DTTs) and methanethiosulfonates (MTSs). These were evaluated as STAT3 inhibitors since these electrophilic systems could react with thio

AGENT FOR PREVENTION AND TREATMENT OF CANCER COMPRISING OXADIAZOLE UREA COMPOUND OBSTRUCTING ACTIVITY OF STAT

Disclosed herein is an agent for preventing and treating cancer comprising an oxadiazole urea compound represented by Chemical Formula 1, below, as an effective ingredient. The oxadiazole urea compound effectively inhibits the growth of cancer cell lines

One-pot synthesis of 3-amino-4-aryl- and 3-amino-4-hetarylfurazans

A "one pot" method for the synthesis of 3-amino-4-aryl- and 3-amino-4-hetarylfurazans from β-aryl- and 4-β-hetaryl-β-oxo acid esters was developed.

Novel Syntheses of Heterocycles from α-Ketonitriles: Part II - 3-Amino-4-aryl-1,2,5-oxadiazoles

A general synthesis is described for 3-amino-4-aryl-1,2,5-oxadiazoles (3) by treatment of aroyl cyanides (1) with hydroxylamine hydrochloride in the presence of anhyd. sodium acetate.A plausible reaction mechanism involving the intermediacy of α-amino-α'-