21741-98-0Relevant articles and documents
N -Oxide-Controlled Chemoselective Reduction of Nitrofuroxans
Fershtat, Leonid L.,Bystrov, Dmitry M.,Zhilin, Egor S.,Makhova, Nina N.
, p. 747 - 756 (2019/01/23)
A facile and chemoselective SnCl 2 -mediated mild reduction of regioisomeric 3- and 4-nitrofuroxans for the synthesis of aminofurazans and aminofuroxans in good yields is developed. Reduction of 4-nitrofuroxans results in the selective formation of 4-aminofuroxans, while analogous reduction of 3-nitrofuroxans affords 3-aminofurazans as a result of simultaneous reduction of the nitro group and exocyclic N-O bond.
Synthesis of new dithiolethione and methanethiosulfonate systems endowed with pharmaceutical interest
Gabriele, Elena,Porta, Federica,Facchetti, Giorgio,Galli, Corinna,Gelain, Arianna,Meneghetti, Fiorella,Rimoldi, Isabella,Romeo, Sergio,Villa, Stefania,Ricci, Chiara,Ferri, Nicola,Asai, Akira,Barlocco, Daniela,Sparatore, Anna
, p. 235 - 250 (2017/03/09)
Here we report synthetic methodology affording in the most efficient way the rapid preparation of new dithiolethiones (DTTs) and methanethiosulfonates (MTSs). These were evaluated as STAT3 inhibitors since these electrophilic systems could react with thio
One-pot synthesis of 3-amino-4-aryl- and 3-amino-4-hetarylfurazans
Sheremetev
, p. 1057 - 1059 (2007/10/03)
A "one pot" method for the synthesis of 3-amino-4-aryl- and 3-amino-4-hetarylfurazans from β-aryl- and 4-β-hetaryl-β-oxo acid esters was developed.