7541-33-5Relevant academic research and scientific papers
Preparation of Disubstituted Maleic Anhydrides from Reactive 2-Oxo-3H-imidazopyridinium Compounds
Baumann, Marcus E.,Bosshard, Hans,Breitenstein, Werner,Rist, Guenter
, p. 396 - 403 (1986)
A new useful method for the preparation of disubstituted maleic anhydrides, most of them bearing additional functional groups in the side chain, is described.The key step of the synthesis consists of the addition of 2-oxo-3H-imidazopyridinium compounds to a variety of different Michael acceptors.
A New Approach to Rethrolone Synthesis
Jondiko, Isaac J. O.,Pattenden, Gerald
, p. 467 - 470 (2007/10/02)
Rearrangement of the 4-ylidenebutenolides (4) and (5), with sodium methoxide in methanol, leads to the cyclopent-2-ene-1,4-diones (6), which when heated with sodium chloride in dimethyl sulphoxide give the 1,4-diones (7).The latter can be reduced using zinc in acetic acid, to the dihydroethrolones (8).In a similar manner, rearrangement of (10) produces (11a) which can be demethoxycarbonylated to (11b), an intermediate used previously in a synthesis of natural jasmololone (8; R = EtCH:CH).
