75414-58-3Relevant academic research and scientific papers
Synthesis of 4-Nitrophenyl Esters of Thymidine 3'-Phosphate and 3'-Phosphorothioate using a New Phosphorylating Agent
Niewiarowski, Wojcieh,Stec, Wojcieh J.,Zielinski, Wojcieh S.
, p. 524 - 525 (2007/10/02)
2'-Desoxynucleoside-3'-O-(4-nitrophenyl) phosphoranilidates (e.g., 2), prepared by the action of O-(4-nitrophenyl) N-phenylphosphoramidochloridate (1) on alcohols, are converted into the corresponding 4-nitrophenyl phosphate esters (e.g., 3) or P-chiral 4-nitrophenyl phosphorothioate esters (e.g., 4) by treatment with NaH-CX2 (X = O or S).
