75414-47-0

Upstream product

• 777-52-6 1-dichlorophosphoryloxy-4-nitro-benzene 
• 62-53-3 aniline 

Downstream Products

• 75414-59-4 Phenyl-phosphoramidic acid (2R,3S,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 4-nitro-phenyl ester 
• 75414-58-3 Phenyl-phosphoramidic acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 4-nitro-phenyl ester 
• 75414-57-2 Phenyl-phosphoramidic acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 4-nitro-phenyl ester 
• 75414-48-1 5'-O-monomethoxytritylthymidine 3'-O-(4-nitrophenyl) phosphoranilidate 
• 76746-46-8 3'-Monomethoxytrityl-5'-(4-nitrophenyl N-phenyl phosphoramidate) thymidine 
• 76746-45-7 3'-Monomethoxytrityl-5'-(4-nitrophenyl N-phenyl phosphoramidate) thymidine 
• 16562-50-8 thymidine 3'-O-(4-nitrophenyl)phosphate 
• 108782-83-8 (S)-Thiophosphoric acid O-{(2R,3S,5R)-5-(6-amino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester S-methyl ester O'-(4-nitro-phenyl) ester 
• 108782-82-7 (R)-Thiophosphoric acid O-{(2R,3S,5R)-5-(6-amino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester S-methyl ester O'-(4-nitro-phenyl) ester 
• 108782-85-0 (R)-Phenyl-phosphoramidic acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl ester 4-nitro-phenyl ester 
• 108782-86-1 (S)-Phenyl-phosphoramidic acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl ester 4-nitro-phenyl ester 
• 126354-79-8 5'-O-monomethoxytritylthymidine 3'-O- 
• 126354-79-8 (S)-Thiophosphoric acid O-[(2R,3S,5R)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester S-(2-nitro-benzyl) ester O'-(4-nitro-phenyl) ester 

Relevant academic research and scientific papers

Synthesis of 4-Nitrophenyl Esters of Thymidine 3'-Phosphate and 3'-Phosphorothioate using a New Phosphorylating Agent

2'-Desoxynucleoside-3'-O-(4-nitrophenyl) phosphoranilidates (e.g., 2), prepared by the action of O-(4-nitrophenyl) N-phenylphosphoramidochloridate (1) on alcohols, are converted into the corresponding 4-nitrophenyl phosphate esters (e.g., 3) or P-chiral 4-nitrophenyl phosphorothioate esters (e.g., 4) by treatment with NaH-CX2 (X = O or S).

SYNTHESES AND CONFIGURATIONAL ASSIGNMENTS OF THE DIASTEREOMERS OF THE 4-NITROPHENYL ESTERS OF THYMIDINE 3'-(N-PHENYL PHOSPHORAMIDATE) AND THYMIDINE 5'-(N-PHENYL PHOSPHORAMIDATE)

The separated diastereomers of 3'-(4-nitrophenyl N-phenyl phosphoramidate)-5'-monomethoxytrityl thymidine and 3'-monomethoxytrityl-5'-(4-nitrophenyl N-phenyl phosphoramidate) thymidine have been prepared and their absolute configurations at phosphorus hav